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image: Dengue Infection Impairs Immune Defense Against Zika

Dengue Infection Impairs Immune Defense Against Zika

By | August 18, 2017

A memory B cell response to Zika virus in dengue-infected patients produced antibodies that were poorly neutralizing in vitro and instead enhanced infection.

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image: The Ever-Expanding T-Cell World: A Primer

The Ever-Expanding T-Cell World: A Primer

By | August 7, 2017

Researchers continue to identify new T-cell subtypes—and devise ways to use them to fight cancer. The Scientist attempts to catalog them all.

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image: Fascinated by Folding

Fascinated by Folding

By | August 4, 2017

Lila Gierasch uses biochemical tools to understand how linear chains of amino acids turn into complex three-dimensional structures.

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image: Resistance to HIV Engineered Via CRISPR

Resistance to HIV Engineered Via CRISPR

By | August 3, 2017

Mice transplanted with human hematopoietic stem cells that have an HIV receptor gene, CCR5, disrupted by gene editing allows the animals to ward off HIV infection. 

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A new method stimulates B cells to make human antigen-specific antibodies, obviating the need for vaccinating blood donors or hunting for rare B cells.

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Another case of HIV remission emerges, this time in a South African girl diagnosed as an infant and disease-free for more than eight years.

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image: Mammalian Immunity: What’s RNAi Got to Do with It?

Mammalian Immunity: What’s RNAi Got to Do with It?

By | July 21, 2017

A new study adds to the evidence that mammalian cells can use small interfering RNAs to defend against viruses, but questions remain about physiological importance.

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image: Immunized Cows Produce Anti-HIV Antibodies

Immunized Cows Produce Anti-HIV Antibodies

By | July 20, 2017

Cows injected with a protein that mimics HIV’s envelope make broadly neutralizing antibodies that inhibit multiple strains of the virus.

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image: Demonstrating Discontent, May 21, 1990

Demonstrating Discontent, May 21, 1990

By | July 17, 2017

Activists demanded greater access to and involvement in clinical research for AIDS treatments—and their protests were heard.

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Using single-cell RNA sequencing, scientists characterize new populations of dendritic cells and monocytes.

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