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image: Next Generation: Designer Cells Treat Psoriasis

Next Generation: Designer Cells Treat Psoriasis

By | December 16, 2015

Engineered cells detect early biomarkers of a psoriasis flare-up in mice and release compounds to soothe or prevent the skin reaction.

1 Comment

image: Fanning the Flames

Fanning the Flames

By | November 1, 2015

Obesity triggers a fatty acid synthesis pathway, which in turn helps drive T cell differentiation and inflammation.

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image: The 6,000-Calorie Diet

The 6,000-Calorie Diet

By | November 1, 2015

Overeating and inactivity lead to insulin resistance in just days—and oxidative stress is to blame.

2 Comments

image: Breaking the Cancer-Obesity Link

Breaking the Cancer-Obesity Link

By , , and | November 1, 2015

Obese people are at higher risk for developing cancer, have worse prognoses once diagnosed, and are often resistant to chemotherapy regimens. The question is, Why?

2 Comments

image: A Complex Disorder

A Complex Disorder

By , , and | November 1, 2015

Factors that likely contribute to obesity include disruptions to intercellular signaling, increased inflammation, and changes to the gut microbiome.  

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image: Not Immune to Fat

Not Immune to Fat

By | November 1, 2015

The effect of a high-fat diet on murine T cells

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image: B Cells Can Drive Inflammation in MS

B Cells Can Drive Inflammation in MS

By | October 21, 2015

Researchers identify a subset of proinflammatory cytokine-producing B cells that may spark multiple sclerosis-related inflammation.  

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image: Dengue’s Downfall?

Dengue’s Downfall?

By | September 15, 2015

Researchers characterize a protein that could be key to the virus’s virulence—and to developing a vaccine against the mosquito-borne disease.

0 Comments

image: Body, Heal Thyself

Body, Heal Thyself

By | September 1, 2015

Reviving a decades-old hypothesis of autoimmunity

8 Comments

image: How Fats Influence the Microbiome

How Fats Influence the Microbiome

By | August 27, 2015

Mice fed a diet high in saturated fat show shifts in their gut microbes and develop obesity-related inflammation.

1 Comment

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