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image: Resolving Chronic Pain

Resolving Chronic Pain

By | January 1, 2012

The body’s own mechanism for dispersing the inflammatory reaction might lead to new treatments for chronic pain.

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Contributors

January 1, 2012

Meet some of the people featured in the January 2012 issue of The Scientist.

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image: Inflammation, Pain, and Resolvins

Inflammation, Pain, and Resolvins

By | January 1, 2012

Not all inflammation leads to pain. Despite widespread infection followed by fever, colds rarely cause pain. But when some cytokines and certain immune cells are active near pain-sensing nerves, they trigger receptors that convey pain sensations to the brain.

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image: Punch Drunk

Punch Drunk

By | December 1, 2011

After a concussion forces him to retire, a former pro-wrestler starts an institute to study the neurological effects of repeated brain injuries.

18 Comments

image: Immunologists Take Home Nobel

Immunologists Take Home Nobel

By | October 3, 2011

The Nobel Assembly announced today that three researchers in the field of immunology will share the 2011 Prize in Physiology or Medicine.

45 Comments

image: Three Share 2011 Medicine Nobel

Three Share 2011 Medicine Nobel

By | October 3, 2011

The Nobel Assembly reveals three winners of this year's prize in Physiology of Medicine.

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image: Neurotransmitter-Regulated Immunity

Neurotransmitter-Regulated Immunity

By | September 15, 2011

Nerve signals control T cell responses, helping to explain inflammation and stroke.

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image: What Causes Alzheimer’s?

What Causes Alzheimer’s?

By | September 1, 2011

Researchers and pharma companies have tried to attack this disease by reducing amyloid plaques, but inflammation may be the real culprit.

39 Comments

image: Piggyback Pathogen

Piggyback Pathogen

By | September 1, 2011

Editor’s Choice in Immunology

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image: The Cytokine Cycle

The Cytokine Cycle

By | September 1, 2011

The initiating cause of Alzheimer’s disease is still unknown. However, from our studies it’s clear that many types of neuronal damage—­­from traumatic brain injury, to epilepsy, infection, or genetic predisposition—­can activate brain immune cells—microglia and astrocytes-- promoting them to produce IL-1 and S100 inflammatory cytokines.

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