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image: Q&A: What’s Next for PLOS

Q&A: What’s Next for PLOS

By | December 27, 2016

A conversation with outgoing Chief Executive Officer Elizabeth Marincola

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Oncologists have raised concerns about a mouse study that suggests the vaccine for human papillomavirus could cause brain damage.

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image: Oligonucleotide Therapeutics Near Approval

Oligonucleotide Therapeutics Near Approval

By | December 1, 2016

Successful late-stage clinical trials could mark the maturation of a new drug development platform, but the path to commercialization is not without hurdles.

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image: More Success Fixing Sickle Cell Gene with CRISPR

More Success Fixing Sickle Cell Gene with CRISPR

By | November 9, 2016

Researchers say they have sufficient in vitro and animal data to apply for human testing.

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Family members with a certain gene variant had unnecessary interventions, highlighting the potential hazards of precision medicine.

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image: Zika Update

Zika Update

By | October 24, 2016

Virus’s effect on RNA methylation; identifying brain cells targeted by Zika; virus found in vaginal secretions for two weeks after infection; updated CDC recommendations for Miami

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image: European Drug Regulator Releases Clinical Trial Data

European Drug Regulator Releases Clinical Trial Data

By | October 21, 2016

In the initial steps of a campaign to make clinical reports publicly available, the European Medicines Agency has published data on two recently approved drugs.

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image: Nixing NETs to Prevent Metastasis

Nixing NETs to Prevent Metastasis

By | October 19, 2016

Researchers discover that neutrophil extracellular traps help cancers spread, and design enzyme-loaded nanoparticles to destroy them.

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Once implanted in mice, the edited stem cells produced normal hemoglobin.

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image: Clinical Trial Database Launches

Clinical Trial Database Launches

By | October 12, 2016

OpenTrials.net seeks to increase transparency and make clinical research more accessible to the public.

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