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image: The Challenges of Rare-Disease Research

The Challenges of Rare-Disease Research

By | September 1, 2016

With few resources and hesitant investors, basic scientists must rely on clinicians, patient advocates, and their own keen eye for biological connections.

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image: One Receptor, Two Ligands, Different Responses

One Receptor, Two Ligands, Different Responses

By | August 31, 2016

Host and bacterial ligands that interact with the same cell-surface receptor induce different activities in human macrophages. 

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image: One Antigen Receptor Induces Two T cell Types

One Antigen Receptor Induces Two T cell Types

By | August 26, 2016

Precursor T cells bearing the same antigen receptor adopt two different fates in mice.

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image: Physical Force Upregulates Gene Expression

Physical Force Upregulates Gene Expression

By | August 24, 2016

Applying a mechanical force that pulls on a cell stretches chromatin, facilitating transcription, scientists show.

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image: Polio Reemerges in Nigeria

Polio Reemerges in Nigeria

By | August 15, 2016

Prior to last week’s announcement of newly confirmed cases, the country had been polio-free for two years.

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image: Moving Toward Personalized Autism Treatment

Moving Toward Personalized Autism Treatment

By | August 1, 2016

Researchers aim to leverage new insights into the underlying causes of the disorder to better help patients. 

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image: On Becoming Human

On Becoming Human

By | August 1, 2016

Some thoughts on going to the Galápagos

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image: Humans Never Stopped Evolving

Humans Never Stopped Evolving

By | August 1, 2016

The emergence of blood abnormalities, an adult ability to digest milk, and changes in our physical appearance point to the continued evolution of the human race.

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image: The Genes Underlying Autism Are Coming Into Focus

The Genes Underlying Autism Are Coming Into Focus

By | August 1, 2016

As researchers sequence the DNA of thousands of kids with autism, dozens of genetic subgroups are emerging.

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image: Contributors

Contributors

By | August 1, 2016

Meet some of the people featured in the August 2016 issue of The Scientist.

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