cell & molecular biology

After 6 months in orbit, Caenorhabditis elegans return to Earth—alive and well.

Full Professor and Senior Research Group Leader, German Center for Neurodegenerative Diseases. Age: 42

Through a series of sustained collaborations, Joshua Sanes has deciphered the molecular synergy that guides synapse formation.

Researchers find that newts are capable of regenerating body parts well into old age.

Cut off a newt’s tail or a leg, or remove a lens from its eye, and it grows back. However, whether newts can continue to do this throughout their lives, or lose the ability as they get older, has remained a mystery. 

The tongue may be the epicenter of taste sensation, but taste receptors are scattered throughout the digestive and respiratory tracts.

Advances in cell-culture technologies are paving the way to the complete elimination of animals from the laboratory.

Editor’s choice in Cell Biology

Compounds we perceive as sweet or bitter in the mouth trigger similar receptors and signaling pathways elsewhere in the body, helping to regulate digestion, respiration, and other systems.

Researchers identify common genetic changes in cultured human embryonic stem cells, including one that confers a growth advantage.

The behavior of skin stem cells is regulated by a 24-hour circadian clock.

Researchers have developed a way to activate cancer fighting drugs by pulsing them with light, which could make such therapies safer.

An alternative form of an enzyme involved in the glucose metabolism pathway protects cancer cells from oxidative stress.

By selectively killing senescent cells, researchers can slow the decline of health in aging mice.

A snapshot of the most highly ranked articles in molecular biology and related areas, from Faculty of 1000

Researchers have pinpointed the region of a key cancer gene that’s involved in tumor suppression.

Bacteria age, but as a lineage, can live forever.

Researchers show that the bacterial species in probiotic, fermented dairy products may alter gene expression and metabolism in native gut microbiota.

A snapshot of the most highly ranked articles in biochemistry and related areas, from Faculty of 1000

A group of microRNAs can inhibit the formation of induced pluripotent stem cells, and may provide a target for more efficient reprogramming of somatic cells.