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tag basal cell carcinoma genetics genomics

A fishing cat with a fish in its mouth
Genome Spotlight: Fishing cat (Prionailurus viverrinus)
Christie Wilcox, PhD | Dec 22, 2022 | 5 min read
A high-quality reference genome for this vulnerable feline may help scientists understand why they’re so prone to transitional cell carcinoma in captivity.
Tagged for Cleansing
Michele Pagano | Jun 1, 2009 | 10+ min read
Tagged for Cleansing Not just the cell's trash and recycling center, the ubiquitin system controls complex cellular pathways with elegant simplicity and precision. By Michele Pagano have always gravitated toward order. I may even take it a bit too far according to friends who liken my office to a museum. However, I like to think it not a compulsion, but a Feng Shui approach to life. With this need for order, I may have been better suited to
Making Things Grow: Insect Cells, Stem Cells, and Primary Cell Lines All Pose Challenges for Cell Culturists
Laura Defrancesco | Jun 21, 1998 | 5 min read
Date: June 22, 1998 Insect Cell Culture Media, Suppliers of Primary Cell Culture Media Advantages for Protein Expression Studies Since the mid-1950s cultures of insects--cockroaches, fruit flies, and leafhoppers, to name a few--have been the object of quiet study by physiologists and cell biologists. But along came genetic engineering and suddenly insect cultures have been put in the spotlight since they provide advantages over both bacterial and mammalian systems for recombinant protein prod
Cancer Kismet
Jenny Rood | Apr 1, 2015 | 4 min read
Fate mapping allows researchers to follow cancer progression from its cell type of origin.
More Than Skin Deep
Anna Azvolinsky | May 1, 2016 | 9 min read
Elaine Fuchs has worked on adult stem cells since before they were so named, figuring out how multipotent epidermal cells renew or turn into skin or hair follicles.
Autophagy Revisited
Bob Grant | Mar 1, 2008 | 4 min read
Even healthy cells require this catabolic process.
Don't Clone Alone
Laura Defrancesco | Sep 14, 1997 | 10 min read
Date: September 15, 1997 cDNA Library Kit Table and Species Chart Pre-made cDNA libraries and kits abound in the market to help you probe the secrets of gene regulation while minimizing the drudgery of cDNA library construction. The ability to analyze a cell's genetic read-out-to determine which of the 100,000 possible genes are actually being expressed in a cell or tissue-is to know what makes a cell what it is. This is a central issue in molecular biology. For decades, cDNA libraries-colle
Aberrant Signaling
Linda Schultz | Sep 21, 2003 | 9 min read
Dissecting the mechanisms of cancer has revealed an ever-increasing number of interconnecting pathways that leaves even those in the field dizzy with the effort to keep up. In theory, it's simple. In an ideal world, cell division, survival, and death are in sync, promoting homeostasis with neither unregulated growth nor inappropriate cell loss. However, the real cellular world is laden with oncogenes and tumor suppressor genes whose products interact in overlapping pathways that, when dysfunct
The Lessons of Beneficial Chromosomes
Arielle Emmett | Jul 23, 2000 | 4 min read
In mid-April the Department of Energy (DOE) stole thunder from the National Institutes of Health when it announced the draft decoding of DNA on human chromosomes 5, 16, and 19. Containing an estimated 10,000-15,000 genes, the chromosomes constitute 300 million bases, or an estimated 11 percent of the total human genome. Genes on chromosomes 5, 16, and 19 have been linked to certain forms of kidney disease, prostate and colorectal cancer, leukemia, hypertension, diabetes, and atherosclerosis. But
Top 7 in Molecular Biology
Cristina Luiggi | Aug 16, 2011 | 3 min read
A snapshot of the most highly ranked articles in molecular biology, from Faculty of 1000

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