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tag drosophila immunology

A Look at Drosophila Pattern Formation
Jeffrey Perkel | Sep 2, 2001 | 9 min read
Researchers interested in gene expression studies adopt one of two approaches. They can either examine the expression of a given gene in a population of cells in aggregate, or they can study the gene on a cell-by-cell basis in situ. The advantage of the former approach is its simplicity: It is generally easy to prepare RNA or protein from a given tissue sample and to probe it for the gene or protein of interest. But there are several disadvantages associated with the population approach. First o
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky | Mar 1, 2018 | 10+ min read
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
Immune to Failure
Karen Hopkin | Feb 1, 2013 | 9 min read
With dogged persistence and an unwillingness to entertain defeat, Bruce Beutler discovered a receptor that powers the innate immune response to infections—and earned his share of a Nobel Prize.
Schistosomiasis under scrutiny
Cathy Holding(cholding@hgmp.mrc.ac.uk) | Sep 14, 2003 | 2 min read
Schistosome transcriptome analysis identifies novel genes that could form basis for a vaccine
Making Things Grow: Insect Cells, Stem Cells, and Primary Cell Lines All Pose Challenges for Cell Culturists
Laura Defrancesco | Jun 21, 1998 | 5 min read
Date: June 22, 1998 Insect Cell Culture Media, Suppliers of Primary Cell Culture Media Advantages for Protein Expression Studies Since the mid-1950s cultures of insects--cockroaches, fruit flies, and leafhoppers, to name a few--have been the object of quiet study by physiologists and cell biologists. But along came genetic engineering and suddenly insect cultures have been put in the spotlight since they provide advantages over both bacterial and mammalian systems for recombinant protein prod
60 Members Elected to NAS
Barry Palevitz | Jun 25, 2000 | 6 min read
Editor's Note: On May 2, the National Academy of Sciences announced the election of 60 new members and 15 foreign associates from nine countries in recognition of their distinguished and continuing achievements in original research. Nearly half of the new members are life scientists. In this article, The Scientist presents photographs of some of the new members and comments from a few of them on their careers and on past and current research. A full directory of NAS members can be found online a
Creative Expression: Mammalian Expression Vectors and Systems
Christopher Smith | Feb 1, 1998 | 7 min read
Date: February 2, 1998 Chart 1 Chart 2 Prokaryotic expression systems, reviewed in the September 1, 1997, issue of The Scientist were part of the early repertoire of research tools in molecular biology. Although the expression of recombinant protein in prokaryotes provided a means to develop other research tools (antibodies, for example ) and study basic aspects of biological function, the scope and depth of this research were limited, especially with regard to eukaryotic proteins. The de novo
Flow Cytometry
Josh Roberts | May 4, 2003 | 8 min read
Courtesy of DakoCytomation Conventional wisdom holds that flow cytometers are expensive, massive, high-maintenance instruments that require trained operators. They are plumbed into centralized facilities of large institutions, where investigators can pay to have their cells sorted, or perform the analyses themselves (provided they have the requisite skills) under the watchful eye of the center's personnel. But as so often happens, the conventional wisdom is wrong. Nowadays, flow cytometers ar
Better Understanding Of Cell's Life Eases Culturing
Ricki Lewis | Nov 13, 1994 | 10+ min read
"Lots of companies come out with media or reagents for this or that, and make a big splash, but they're all basically derivatives of traditional products," says Hayden Coon, a former National Institutes of Health re-searcher who is the founder of Human Cell Therapies Inc. of Chebeague Island, Maine. Advanced Biotechnologies Inc. Columbia, MD American Qualex Antibodies La Mirada, CA American Type Culture Collection (ATCC) Rockv
Better Understanding Of Cell's Life Eases Culturing
Ricki Lewis | Nov 13, 1994 | 10+ min read
"Lots of companies come out with media or reagents for this or that, and make a big splash, but they're all basically derivatives of traditional products," says Hayden Coon, a former National Institutes of Health re-searcher who is the founder of Human Cell Therapies Inc. of Chebeague Island, Maine. Advanced Biotechnologies Inc. Columbia, MD American Qualex Antibodies La Mirada, CA American Type Culture Collection (ATCC) Rockv

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