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tag bioinformatics evolution

multicolor DNA sequencing gel
Genetic Mutations Can Be Benign or Cancerous—a New Method to Differentiate Between Them Could Lead to Better Treatments
Ryan Layer, The Conversation | May 27, 2022 | 5 min read
Tumors contain thousands of genetic changes, but only a few are actually cancer-causing. A quicker way to identify these driver mutations could lead to more targeted cancer treatments.
Tag, You're It
Carina Storrs | Feb 1, 2014 | 7 min read
A guide to DNA-encoded libraries for drug discovery
Illustration showing a puzzle piece of DNA being removed
Large Scientific Collaborations Aim to Complete Human Genome
Brianna Chrisman and Jordan Eizenga | Sep 1, 2022 | 10+ min read
Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.
Checking the Alignment
Jane Salodof Macneil | Sep 21, 2003 | 9 min read
Courtesy of European Bioinformatics Institute  KNOWLEDGE GAPS? Sequence alignments offer clues to both the function and evolution of novel genes. But a bewildering array of algorithms and parameters leaves many researchers unable to use these programs to their fullest potential. In the beginning, there was Needleman-Wunsch, which begat Smith-Waterman, which begat FASTA, which begat BLAST, and so on. Peel away the information technology jargon surrounding these alignment algorithms, and a
The Genetics of Society
Claire Asher and Seirian Sumner | Jan 1, 2015 | 10 min read
Researchers aim to unravel the molecular mechanisms by which a single genotype gives rise to diverse castes in eusocial organisms.
Human Genes: How Many?
Tom Hollon | Oct 14, 2001 | 6 min read
Counting human genes ought to be straightforward. Tracking telltale signs--motifs for promoters, translation start sites, splice sites, CpG islands--gene counters must by now be mopping up, finalizing chromosomal locations of every human gene already known, and predicting whereabouts of all the rest. Insert one human genome sequence, turn the bioinformatics crank, and genes gush out like a slot machine jackpot, right? "No, no, no," says Bo Yuan, of Ohio State University, having a laugh over th
Making DNA Data Storage a Reality
Catherine Offord | Oct 1, 2017 | 10+ min read
A few kilograms of DNA could theoretically store all of humanity’s data, but there are practical challenges to overcome.
Top 10 Innovations 2014
The Scientist | Dec 1, 2014 | 10+ min read
The list of the year’s best new products contains both perennial winners and innovative newcomers.
Plant genomics gets $100 million infusion
Charles Choi(cqchoi@nasw.org) | Oct 7, 2003 | 3 min read
New NSF-funded virtual centers created to cultivate speedy collaboration
Games for Science
The Scientist | Jan 1, 2013 | 10+ min read
Scientists are using video games to tap the collective intelligence of people around the world, while doctors and educators are turning to games to treat and teach.

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