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image: CRISPR Used in Human Embryos to Probe Gene Function

CRISPR Used in Human Embryos to Probe Gene Function

By | September 20, 2017

OCT4 is necessary for blastocyst formation in the human embryo, researchers report.

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image: Cell Lines Gain Cancer-Related Mutations

Cell Lines Gain Cancer-Related Mutations

By | April 27, 2017

A screen of human embryonic stem cell lines finds several that accumulated changes in the gene TP53, including aberrations commonly seen in cancer.

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image: First Clinic-Ready Stem Cell Repository

First Clinic-Ready Stem Cell Repository

By | April 6, 2017

The UK Stem Cell Bank offers several lines derived from human embryonic tissue.

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Scientists issue a call to reconsider the rules governing the creation of tissues, organs, and other structures made possible by recent advances in synthetic biology. 

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Removing a specific miRNA from stem cells may induce the expression of endogenous retroviruses that enable the cells to form extra-embryonic lineages.

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image: Stem Cells Made Waves in Biology and Medicine

Stem Cells Made Waves in Biology and Medicine

By | October 1, 2016

Since their introduction to the lab, pluripotent stem cells have gone from research tool to therapeutic, but the journey has been rocky.

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image: Thirty Years of Progress

Thirty Years of Progress

By | October 1, 2016

Since The Scientist published its first issue in October 1986, life-science research has transformed from a manual and often tedious task to a high-tech, largely automated process of unprecedented efficiency.

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Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

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image: Improving Mitochondrial Replacement Therapy

Improving Mitochondrial Replacement Therapy

By | June 8, 2016

Pronuclear transfer can reduce the risk of transferring defective mitochondria, a study shows.  

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image: Stem Cell Rules Tackle Human Embryo Editing

Stem Cell Rules Tackle Human Embryo Editing

By | May 17, 2016

A set of international stem cell guidelines recommends that oversight committees at research institutions oversee all research on embryos.

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