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tag cloning genetics genomics

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Green and red fluorescent proteins in a zebrafish outline the animal’s vasculature in red and lymphatic system in green in a fluorescent image. Where the two overlap along the bottom of the animal is yellow.
Serendipity, Happenstance, and Luck: The Making of a Molecular Tool
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.
Cool Cloning
Karen Hopkin | Jul 1, 2008 | 7 min read
Lynn Cooley figured she'd study sea creatures, then decided to revolutionize genetics instead.
Histological slide showing cancerous prostate tissue
2D Genetic Map of Prostate Cells Charts Cancer Growth
Holly Barker, PhD | Aug 23, 2022 | 4 min read
An in situ map of copy number variations in prostate tissue reveals that purportedly cancerous genomic changes frequently occur in the healthy tissue surrounding tumors.
Genetics
The Scientist Staff | Jul 10, 1994 | 2 min read
S. Foote, D. Vollrath, A. Hilton, D.C. Page, "The human Y chromosome: Overlapping DNA clones spanning the euchromatic region," Science, 258:60-6, 1992. Simon Foote (Immunoparasitology Unit, Walter and Eliza Hall Institute of Medical Research, Victoria, Australia): "The initial path for the Human Genome Project has been well delineated. Initially, high-resolution maps, both genetic and physical, must be constructed, followed by th
Genetics
The Scientist Staff | Jul 10, 1994 | 2 min read
S. Foote, D. Vollrath, A. Hilton, D.C. Page, "The human Y chromosome: Overlapping DNA clones spanning the euchromatic region," Science, 258:60-6, 1992. Simon Foote (Immunoparasitology Unit, Walter and Eliza Hall Institute of Medical Research, Victoria, Australia): "The initial path for the Human Genome Project has been well delineated. Initially, high-resolution maps, both genetic and physical, must be constructed, followed by th
Advances in the functional characterization of newly discovered microproteins hint at their diverse roles  in health and disease
The Dark Matter of the Human Proteome
Annie Rathore | Apr 1, 2019 | 10 min read
Advances in the functional characterization of newly discovered microproteins hint at diverse roles in health and disease.
The Human Genome
Arielle Emmett | Jul 23, 2000 | 10+ min read
Life sciences took center stage virtually around the world June 26. President Bill Clinton, flanked on the left by Celera Genomics Group president J. Craig Venter and on the right by National Human Genome Research Institute director Francis S. Collins, announced the completion of "the first survey of the entire human genome."
Influential Consortium's cDNA Clones Praised As Genome Research Time-Saver
Karen Young Kreeger | May 14, 1995 | 7 min read
IMAGE group's DNA libraries are made freely available to other researchers, as long as they, too, pass on information to the public. In less than two years, a research initiative begun by four geneticists has grown from an ad hoc collaboration to an international cooperative effort to freely share complementary DNA (cDNA) clone libraries. To date, in excess of 100,000 clones from the Integrated Molecular Analysis of Genome Expression (IMAGE) Consortium have been sent to more than 40 facilities
Don't Clone Alone
Laura Defrancesco | Sep 14, 1997 | 10 min read
Date: September 15, 1997 cDNA Library Kit Table and Species Chart Pre-made cDNA libraries and kits abound in the market to help you probe the secrets of gene regulation while minimizing the drudgery of cDNA library construction. The ability to analyze a cell's genetic read-out-to determine which of the 100,000 possible genes are actually being expressed in a cell or tissue-is to know what makes a cell what it is. This is a central issue in molecular biology. For decades, cDNA libraries-colle

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