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image: Epigenetics of Trained Innate Immunity

Epigenetics of Trained Innate Immunity

By | September 25, 2014

Documenting the epigenetic landscape of human innate immune cells reveals pathways essential for training macrophages.

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image: Methylation Tied to Alzheimer’s

Methylation Tied to Alzheimer’s

By | August 20, 2014

People with the neurodegenerative disease are more likely to have certain epigenetic patterns than those without.

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image: Epigenetic Changes Can Cause Cancer

Epigenetic Changes Can Cause Cancer

By | July 25, 2014

A transgene designed to attract methylation to the promoter of a tumor-suppressor gene leads to tumorigenesis in a mouse model. 

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image: Gestational Malnutrition Affects Offspring’s Sperm

Gestational Malnutrition Affects Offspring’s Sperm

By | July 10, 2014

Mice undernourished during pregnancy can transmit the effects of such nutritional stress to their sons’ germ cells, epigenetically.  

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image: Done with Immunosuppressants

Done with Immunosuppressants

By | July 3, 2014

Adult sickle-cell patients have safely stopped taking their immunosuppressant medication thanks to a new type of blood stem-cell transplant.

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image: Protein Clumps Spread Inflammation

Protein Clumps Spread Inflammation

By | June 22, 2014

ASC specks—protein aggregations that drive inflammation—are released from dying immune cells, expanding the reach of a defense response.

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image: Ancient Apoptosis

Ancient Apoptosis

By | June 9, 2014

Humans and coral share a cell-death pathway that has been conserved between them for more than half a billion years.

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image: Immunology and Neurology Pioneer Dies

Immunology and Neurology Pioneer Dies

By | May 24, 2014

Gerald Edelman, who broke new ground in two distinct fields of life science, has passed away at age 84.

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image: Long-Distance Call

Long-Distance Call

By | May 1, 2014

Neurons may use interferon signals transmitted over great distances to fend off viral infection.

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image: Commander of an Immune Flotilla

Commander of an Immune Flotilla

By | April 1, 2014

With much of his early career dictated by US Navy interests, Carl June drew inspiration from malaria, bone marrow transplantation, and HIV in his roundabout path to a breakthrough in cancer immunotherapy.

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