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image: Methylation Tied to Alzheimer’s

Methylation Tied to Alzheimer’s

By | August 20, 2014

People with the neurodegenerative disease are more likely to have certain epigenetic patterns than those without.

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image: Epigenetic Changes Can Cause Cancer

Epigenetic Changes Can Cause Cancer

By | July 25, 2014

A transgene designed to attract methylation to the promoter of a tumor-suppressor gene leads to tumorigenesis in a mouse model. 

4 Comments

image: Gestational Malnutrition Affects Offspring’s Sperm

Gestational Malnutrition Affects Offspring’s Sperm

By | July 10, 2014

Mice undernourished during pregnancy can transmit the effects of such nutritional stress to their sons’ germ cells, epigenetically.  

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image: Brain Methylation Map Published

Brain Methylation Map Published

By | July 4, 2013

The epigenetic modification of brain cells undergoes great shifts over the course of mouse and human development.

2 Comments

image: An Epi Phenomenon

An Epi Phenomenon

By | December 1, 2012

While exploring the genetics of a rare type of tumor, Stephen Baylin discovered an epigenetic modification that occurs in most every cancer—a finding he’s helping bring to the clinic.

5 Comments

image: Blood Spots Are Epigenetic Time Capsules

Blood Spots Are Epigenetic Time Capsules

By | August 22, 2012

Researchers show that blood spotted onto Guthrie cards, usually at birth, can be a high quality source of methylated DNA for long-term epigenetic studies.

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image: Exercise Alters Epigenetics

Exercise Alters Epigenetics

By | March 6, 2012

Exercise causes short-term changes in DNA methylation and gene expression in muscle tissue that may have implications for type 2 diabetes.

14 Comments

image: Epigenetic Changes in Cancer

Epigenetic Changes in Cancer

By | March 1, 2011

The study of how covalent marks on DNA and histones are involved in the origin and spread of cancer cells is also leading to new therapeutic strategies.

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