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tag library developmental biology evolution

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Tag, You're It
Carina Storrs | Feb 1, 2014 | 7 min read
A guide to DNA-encoded libraries for drug discovery
Combinatorial Libraries: Life's Tinker Toys
Gail Dutton | May 18, 2003 | 9 min read
Courtesy of UC Davis Medical Center  COMBI-KING: Kit Lam brings his expertise in combinatorial chemistry, an innovative technique for creating millions of new chemical compounds in just days, to the UC Davis Cancer Center. It's the new mix and match. In the computer industry, programmers refer to modularity--the ability to shuffle different sections of computer code to create new software. In the life sciences, the modules are peptides or molecular fragments that can be combined to yield
Close up photo of a wing
Unearthing the Evolutionary Origins of Insect Wings
Jef Akst | Apr 4, 2022 | 6 min read
A handful of new studies moves the needle toward a consensus on the long-disputed question of whether insect wings evolved from legs or from the body wall, but the devil is in the details.
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
From the Ground Up
Anna Azvolinsky | Feb 1, 2017 | 8 min read
Instrumental in launching Arabidopsis thaliana as a model system, Elliot Meyerowitz has since driven the use of computational modeling to study developmental biology.
Top Five Institutions in Biological Sciences Doctorate Programs
Karen Young Kreeger | Oct 15, 1995 | 2 min read
Programs Author: Karen Young Kreeger (Ranked by scores on a survey of scholarly quality of program faculty among peers. Scores on a scale of 0 to 5*") Rank Institution Score Biochemistry and Molecular Biology 1 University of California, San Francisco 4.84 2 Massachusetts Institute of Technology 4.83 Stanford University 4.83 3 University of California, Berkeley 4.81 4 Harvard University 4.80 5 Yale University 4.59 Cell and Developmental Biology 1 Massachusetts Institute of Technology 4.86 2 Ro
Targeted Comparative Sequencing Illuminates Vertebrate Evolution
Ricki Lewis | Dec 8, 2002 | 6 min read
Image: Courtesy of Elliott Marguiles  PIPS ON PARADE: Researchers used a MultiPipMaker to show the alignments, expressed as percent identity plots, between a human reference sequence and several other species. This is a 20 kb region surrounding exon 2 of the MET gene. Gap-free alignable segments are represented as horizontal lines along the human reference sequence; the line's height represents the identity of that alignment. Aristotle envisioned humanity as the pinnacle of a "Great Chai
Genetics Models Move Beyond Drosophila and the Humble Lab Mouse
Amber Dance | Sep 1, 2019 | 8 min read
Organisms with unusual genomes are helping scientists investigate gene regulation, evolution, and development.
Book Excerpt from Some Assembly Required
Neil Shubin | Jun 1, 2020 | 4 min read
In the prologue to the book, author Neil Shubin sets the stage for discussing the iterative repurposing that marks several transformational developments throughout evolution.

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