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image: Scanning for SIV’s Sanctuaries

Scanning for SIV’s Sanctuaries

By | May 1, 2015

Whole-body immunoPET scans of SIV-infected macaques reveal where the replicating virus hides.  

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image: Show Me Your Moves

Show Me Your Moves

By | May 1, 2015

Updated classics and new techniques help microbiologists get up close and quantitative.

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image: The Origins of O

The Origins of O

By | May 1, 2015

A strain of HIV that has afflicted more than 100,000 people emerged from gorillas.

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image: Bacterial Taxis Deliver Proteins

Bacterial Taxis Deliver Proteins

By | April 28, 2015

Reengineered protein-shuttling machinery can be used to inject a particular protein into mammalian cells, according to a proof-of-principle study.

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image: How a Popular Probiotic Works

How a Popular Probiotic Works

By | April 16, 2015

Eating a type of bacterium encourages the activity of other gut microbes, according to a small study.

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image: Enzyme Improves CRISPR

Enzyme Improves CRISPR

By | April 1, 2015

A smaller Cas9 protein enables in vivo genome engineering via viral vectors.

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image: Book Excerpt from <em>p53</em>

Book Excerpt from p53

By | April 1, 2015

In Chapter 12, "Of Mice and Men," author Sue Armstrong recounts the point at which researchers moved from working with p53 in tissue culture to studying the gene in animal models.

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image: Manipulative Microbiomes

Manipulative Microbiomes

By | April 1, 2015

Gut bacteria control tumor growth via the mammalian immune system.

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image: Setbacks and Great Leaps

Setbacks and Great Leaps

By | April 1, 2015

The tale of p53, a widely studied tumor suppressor gene, illustrates the inventiveness of researchers who turn mishaps into discoveries.

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image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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