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image: Book Excerpt from <em>p53</em>

Book Excerpt from p53

By | April 1, 2015

In Chapter 12, "Of Mice and Men," author Sue Armstrong recounts the point at which researchers moved from working with p53 in tissue culture to studying the gene in animal models.

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image: Setbacks and Great Leaps

Setbacks and Great Leaps

By | April 1, 2015

The tale of p53, a widely studied tumor suppressor gene, illustrates the inventiveness of researchers who turn mishaps into discoveries.

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image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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image: Protein Helps Cells Adapt—or Die

Protein Helps Cells Adapt—or Die

By | July 3, 2014

Scientists show how cell stress both prevents and promotes cell suicide in a study that’s equally divisive.

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image: Week in Review: June 9–13

Week in Review: June 9–13

By | June 13, 2014

Ancient apoptotic pathway connects humans to coral; lab-grown, light-sensing retinal tissue; tracking cancer with synthetic phospholipids; diving deep into the lung microbiome

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image: Ancient Apoptosis

Ancient Apoptosis

By | June 9, 2014

Humans and coral share a cell-death pathway that has been conserved between them for more than half a billion years.

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image: Caught on Camera

Caught on Camera

By | May 1, 2014

Selected Images of the Day from www.the-scientist.com

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image: Autophagy Revives Dying Cancer Cells

Autophagy Revives Dying Cancer Cells

By | April 7, 2014

Self digestion thwarts self destruction.  

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image: Polymer Protects Mouse Heart

Polymer Protects Mouse Heart

By | January 20, 2014

Injection of microscopic particles of a plastic-like material protects mice from cardiac tissue damage following heart attack.

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image: Why Many Birds Don’t Have Penises

Why Many Birds Don’t Have Penises

By | June 7, 2013

In avian species, a gene induces programmed cell death during development in the area where a phallus would otherwise grow.

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