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tag linear regression disease medicine

Illustration showing the upper part of a human body connected to a DNA helix
Unraveling the Mystery of Zombie Genes
Iris Kulbatski, PhD | Oct 31, 2023 | 6 min read
Digging into how and why some genes are resurrected after death sounds morbid, but it has practical applications. 
Illustration showing a puzzle piece of DNA being removed
Large Scientific Collaborations Aim to Complete Human Genome
Brianna Chrisman and Jordan Eizenga | Sep 1, 2022 | 10+ min read
Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.
2020 Top 10 Innovations
The Scientist | Dec 1, 2020 | 10+ min read
From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.
masked teacher sitting on floor showing masked students something on a tablet
Does Science Support Lifting School Mask Mandates?
Rachael Moeller Gorman | Feb 28, 2022 | 10+ min read
The CDC has given the OK to lift indoor mask mandates in much of the US, and a growing number of states no longer require face coverings in schools. But most experts agree that masks slow school spread of SARS-CoV-2, and whether now is the right time to allow teachers and students to unmask is a matter of debate.
Building Nanoscale Structures with DNA
Arun Richard Chandrasekaran | Jul 16, 2017 | 10+ min read
The versatility of geometric shapes made from the nucleic acid are proving useful in a wide variety of fields from molecular computation to biology to medicine.
Updated July 9
Track COVID-19 Vaccines Advancing Through Clinical Trials
The Scientist | Apr 7, 2020 | 10+ min read
Find the latest updates in this one-stop resource, including efficacy data and side effects of approved shots, as well as progress on new candidates entering human studies.
Telomeres as the Key to Cancer
Jeffrey Perkel | May 26, 2002 | 9 min read
The standard modus operandi for modeling human diseases in the mouse: Find an interesting gene, knock it out, and watch what happens. In theory, the approach makes perfect sense, and scientists have obtained countless subtle insights into the complexities of biology because of it. But mice, of course, are not humans, and many investigators have had to hastily rewrite otherwise elegant theories because of mouse data. One reason? Researchers have taken for granted that telomere length matters. But
Whole-Genome SNP Genotyping
Marilee Ogren | Jun 1, 2003 | 8 min read
Clockwise from top left: images courtesy of Affymetrix, Illumina, Sequenom and Illumina Take any two individuals, sequence and compare their genomic DNA, and you'll find that the vast majority (about 99.9%) of the sequences are identical. In the remaining 0.1% lie differences in disease susceptibility, environmental response, and drug metabolism. Researchers are understandably keen to dissect these variations, most of which take the form of single-nucleotide polymorphisms (SNPs). A SNP (pron
Variations on a Gene
Amy Francis | Jul 23, 2000 | 10+ min read
Photodisc Although President Bill Clinton surely had something in mind during his 2000 State of the Union address when he asked the nation to "celebrate our diversity," insights into human diversity at the molecular level are promising to speed drug discovery and revolutionize medicine to mark- edly improve human health. Individuals differ at one in 1,000 base pairs, which adds up to a whopping number of human genetic variations when applied to the roughly three billion base pairs of the human g
Imagining a Cure
Nicholas P. Restifo and Megan Bachinski | Apr 10, 2011 | 5 min read
For cancer patients, close is not good enough.

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