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image: Signaling Resistance

Signaling Resistance

By | April 1, 2015

Activating signaling pathways, rather than individual genes, reveals roles for both growth and dedifferentiation in establishing resistance to cancer treatments.

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image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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image: Yvonne Saenger: Immunotherapy Pioneer

Yvonne Saenger: Immunotherapy Pioneer

By | April 1, 2015

Assistant Professor, Department of Medicine, Columbia University. Age: 41

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image: From Many, One

From Many, One

By | April 1, 2015

Diverse mammals, including humans, have been found to carry distinct genomes in their cells. What does such genetic chimerism mean for health and disease?

4 Comments

image: Resisting Cancer

Resisting Cancer

By | April 1, 2015

If one out of three people develops cancer, that means two others don’t. Understanding why could lead to insights relevant to prevention and treatment.

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image: Fast-Track Peer Review Controversy

Fast-Track Peer Review Controversy

By | March 31, 2015

An editor of the journal Scientific Reports quits in protest of paid, expedited review.

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image: Mass Retraction

Mass Retraction

By | March 27, 2015

BioMed Central retracts 43 papers it had been investigating for evidence of faked peer review.

1 Comment

image: Short, Strong Signals

Short, Strong Signals

By | March 25, 2015

Methylation increases both the activity and instability of the signaling protein Notch.

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image: Irisin Skepticism Goes Way Back

Irisin Skepticism Goes Way Back

By | March 18, 2015

Post-publication peer reviewers had questioned data about the supposed fat-browning enzyme from the get-go.

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image: HHS Rolls Out Public Access Plans

HHS Rolls Out Public Access Plans

By | March 3, 2015

The US Department of Health and Human Services outlines how the National Institutes of Health and its other agencies will make research results public.

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