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tag ubiquitin disease medicine

Brain cell in purple on a black background. Arc mRNAs are labeled green and are mainly localized in the cell nucleus and in the dendrites.
Short-lived Molecules Support Long-term Memory 
Alejandra Manjarrez, PhD | Jun 6, 2023 | 3 min read
A gene essential for information storage in the brain engages an autoregulatory feedback loop to consolidate memory.
On the Chain Gang
Keith D. Wilkinson and David Fushman | Jul 1, 2012 | 10 min read
More than simply helping haul out a cell’s garbage, ubiquitin, with its panoply of chain lengths and shapes, marks and regulates many unrelated cellular processes.
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky | Mar 1, 2018 | 10+ min read
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
The Proteasome: A Powerful Target for Manipulating Protein Levels
John Hines and Craig M. Crews | May 1, 2017 | 10+ min read
The proteasome’s ability to target and degrade specific proteins is proving useful to researchers studying protein function or developing treatments for diseases.
How Bacteria Interfere with Insect Reproduction
Ruth Williams | Feb 28, 2017 | 3 min read
Scientists identify the genes responsible for bacteria-controlled sterility in arthropods.
Meeting of the Minds
Mary Beth Aberlin | Jul 1, 2012 | 3 min read
New changes at The Scientist will ensure that we continue to showcase the best and brightest ideas in the life sciences.
Mafia Wars
Jef Akst | May 31, 2010 | 10+ min read
An increasing amount of data is showing that the cellular battle between pathogens and hosts needs much more than a simple military metaphor to describe it—think undercover infiltration, front organizations, and forced suicide.
Notebook
Eugene Russo | Dec 5, 1999 | 7 min read
Contents Pivotal pump Leptin limbo Clue to obesity Biotech Web site Helping hand Mapping malaria Notebook Pictured above are pigmented bacterial colonies of Deinococcus radiodurans, the most radiation-resistant organism currently known. DEINO-MITE CLEANUP In 1956, investigators discovered a potentially invaluable cleanup tool in an unlikely place. A hardy bacterium called Deinococcus radiodurans unexpectedly thrived in samples of canned meat thought to be sterilized by gamma radiation. The b
TSG101: An Antiviral Target with a Murky Past
Ricki Lewis | Jan 18, 2004 | 5 min read
Viruses hijack a host protein that normally sorts the trash
The Scientist Top Innovations of 2008
Alison McCook | Dec 1, 2008 | 10+ min read
The Scientist Top Innovations of 2008 For the first time, we laud the ten most outstanding new products to hit the life science market. The life sciences move fast. Across the globe, companies are constantly churning out new products that they say will make your research smarter. For six years, we've ranked the vendors of life science equipment in our Life Science Industry Awards. Now, to recognize winning combinations of invention, vision and

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