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Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

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image: Stem Cells Drive Cancer Risk in Mice

Stem Cells Drive Cancer Risk in Mice

By | August 26, 2016

Mutations that arise during stem cell division contribute to the development of cancers in a variety of organs, according to a study.

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Disrupting the light/dark cycles of pregnant mice, researchers observe detrimental effects in the mouths of the animals’ pups.

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image: Zika Infects Adult Neural Progenitors Too

Zika Infects Adult Neural Progenitors Too

By | August 18, 2016

A mouse study shows that the virus has tropism for adult proliferative neural progenitor cells and immature neurons.

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image: NIH Reveals Plan to Fund Human-Animal Chimeras

NIH Reveals Plan to Fund Human-Animal Chimeras

By | August 4, 2016

The public gets to weigh in before the US government lifts its ban on such research.

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image: Nailing Down HAR Function

Nailing Down HAR Function

By | August 1, 2016

A remaining challenge in the study of human accelerated regions (HARs) is establishing their specific functions during development and other biological processes.

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image: Will Organs-in-a-Dish Ever Replace Animal Models?

Will Organs-in-a-Dish Ever Replace Animal Models?

By | July 19, 2016

Increasingly sophisticated tissue organoids can model many aspects of disease, but animal studies retain a fundamental role in research, scientists say. 

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image: Immune Cell–Stem Cell Cooperation

Immune Cell–Stem Cell Cooperation

By , , and | July 1, 2016

Understanding interactions between the immune system and stem cells could pave the way for successful stem cell–based regenerative therapies.

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image: Immune Cells' Roles in Tissue Maintenance and Repair

Immune Cells' Roles in Tissue Maintenance and Repair

By , , and | July 1, 2016

The cells of the mammalian immune system do more than just fight off pathogens; they are also important players in stem cell function and are thus crucial for maintaining homeostasis and recovering from injury.

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image: Plastic Pollutants Can Harm Fish

Plastic Pollutants Can Harm Fish

By | June 6, 2016

European perch larvae exposed to environmentally relevant concentrations of polystyrene particles preferred to eat the microplastics in place of prey, according to a study.

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