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image: Replication Complications

Replication Complications

By | January 18, 2017

An initiative to replicate key findings in cancer biology yields a preliminary conclusion: it’s difficult.

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Clostridium botulinum produces a transcription factor that can aggregate and self-propagate a prion-like form, leading to genome-wide changes in gene expression in E. coli, according to a study.

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Removing a specific miRNA from stem cells may induce the expression of endogenous retroviruses that enable the cells to form extra-embryonic lineages.

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A team of scientists was unable to replicate controversial, high-profile findings published in 2011.

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image: Exploring the Epigenetics of Ethnicity

Exploring the Epigenetics of Ethnicity

By | January 11, 2017

Researchers attempt to estimate how much of the human genome’s methylation patterns can be attributed to genetic ancestry.

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Scientists repurpose an Alzheimer’s drug to enhance the ability of stem cells to repair dental damage in mice.

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Contributors

By | January 1, 2017

Meet some of the people featured in the January 2017 issue of The Scientist.

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image: Pharma Redo

Pharma Redo

By | January 1, 2017

Steve Braun of Cures Within Reach, a nonprofit focused on breathing new life into old medicines, describes the potential benefits of drug repurposing.

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Oncologists have raised concerns about a mouse study that suggests the vaccine for human papillomavirus could cause brain damage.

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image: Induced Pluripotent Stem Cells Show Signs of Donor Age

Induced Pluripotent Stem Cells Show Signs of Donor Age

By | December 12, 2016

iPSCs created through the reprogramming of human somatic cells retain genomic marks of the donor’s age.

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