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image: Designing In Vitro Models of the Blood-Brain Barrier

Designing In Vitro Models of the Blood-Brain Barrier

By | September 1, 2016

Choosing the right model, be it 3-D or 2-D, requires wading through varied cell sources, cell types, and cell culture conditions.

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image: The Challenges of Rare-Disease Research

The Challenges of Rare-Disease Research

By | September 1, 2016

With few resources and hesitant investors, basic scientists must rely on clinicians, patient advocates, and their own keen eye for biological connections.

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Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

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image: One Receptor, Two Ligands, Different Responses

One Receptor, Two Ligands, Different Responses

By | August 31, 2016

Host and bacterial ligands that interact with the same cell-surface receptor induce different activities in human macrophages. 

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image: One Antigen Receptor Induces Two T cell Types

One Antigen Receptor Induces Two T cell Types

By | August 26, 2016

Precursor T cells bearing the same antigen receptor adopt two different fates in mice.

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image: Stem Cells Drive Cancer Risk in Mice

Stem Cells Drive Cancer Risk in Mice

By | August 26, 2016

Mutations that arise during stem cell division contribute to the development of cancers in a variety of organs, according to a study.

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image: Zika Infects Adult Neural Progenitors Too

Zika Infects Adult Neural Progenitors Too

By | August 18, 2016

A mouse study shows that the virus has tropism for adult proliferative neural progenitor cells and immature neurons.

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image: Polio Reemerges in Nigeria

Polio Reemerges in Nigeria

By | August 15, 2016

Prior to last week’s announcement of newly confirmed cases, the country had been polio-free for two years.

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image: NIH Reveals Plan to Fund Human-Animal Chimeras

NIH Reveals Plan to Fund Human-Animal Chimeras

By | August 4, 2016

The public gets to weigh in before the US government lifts its ban on such research.

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image: Moving Toward Personalized Autism Treatment

Moving Toward Personalized Autism Treatment

By | August 1, 2016

Researchers aim to leverage new insights into the underlying causes of the disorder to better help patients. 

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