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tag noncoding rna disease medicine culture
The Noncoding Regulators of the Brain
Christie Wilcox, PhD
| Sep 12, 2022
| 10+ min read
Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD
| Mar 15, 2024
| 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Targeting the Noncoding Genome with CRISPR
Anna Azvolinsky
| Sep 29, 2016
| 4 min read
Two independent groups demonstrate the utility of CRISPR-based techniques to identify regulatory elements that govern disease-linked genes.
Book Excerpt from
Deep Medicine
Eric Topol
| Jul 15, 2019
| 4 min read
In Chapter 10, “Deep Discovery,” author Eric Topol considers the marriage of omics and AI.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD
| Sep 8, 2023
| 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Telomeres in Disease
Rodrigo Calado and Neal Young
| May 1, 2012
| 10+ min read
Telomeres have been linked to numerous diseases over the years, but how exactly short telomeres cause diseases and how medicine can prevent telomere erosion are still up for debate.
Short-lived Molecules Support Long-term Memory
Alejandra Manjarrez, PhD
| Jun 6, 2023
| 3 min read
A gene essential for information storage in the brain engages an autoregulatory feedback loop to consolidate memory.
Live and In Color
Sarah Webb,
Knowable Magazine
| Apr 1, 2012
| 7 min read
How to track RNA in living cells
Jumping Genes’ Role in Cancer
Diana Kwon
| Mar 1, 2023
| 8 min read
Transposons may be key players in how tumors develop and spread, but they also keep cancer at bay in some circumstances.
Antisense Oligonucleotides Cross Rodents’ Blood-Brain Barrier
Abby Olena, PhD
| Aug 18, 2021
| 3 min read
RNA-DNA complexes that were modified with cholesterol made it into the brains of rats and mice, where they knocked down target genes.
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