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tag gene therapy immunology disease medicine genetics genomics
Stem Cell Editing Repairs Severe Immunodeficiency
Kamal Nahas, PhD
| Mar 20, 2024
| 5 min read
Scientists hoping to treat immunodeficiencies using gene therapy have found a way to edit stem cells in mice without disrupting gene regulation.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD
| Mar 7, 2024
| 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
Redesigning Medicine Using Synthetic Biology
Alison Halliday, PhD,
Technology Networks
| Jun 21, 2023
| 5 min read
Drawing inspiration from nature, synthetic biology offers exciting opportunities to transform the future of medicine.
New Strategies to Discover Human Disease Genes
The Scientist
| Oct 16, 2023
| 2 min read
Learn how researchers across health-related fields identify and characterize disease-causing genomic variants.
Avoiding Gene Editing’s Unintended Consequences
Tanvir Khan, PhD
| Feb 2, 2024
| 4 min read
CRISPR-Cas9 editing leads to widespread loss of the targeted chromosome in human T cells, but scientists recently discovered a way to prevent such loss.
Jumping Genes Put a Target on Cancerous Cells
Natalia Mesa, PhD
| Feb 14, 2023
| 4 min read
Two studies find that tumor-specific antigens are often peptides that result from a splicing event between exons and transposable elements.
Precision Medicine: A New Era in Cancer Therapy
Rebecca Roberts, PhD
| Dec 15, 2023
| 6 min read
Precision medicine helps clinicians tailor individual treatments, addressing genetic mutations, tumor microenvironment variations, and therapeutic resistance.
The Future of Gene Therapy for a Rare Pediatric Autoimmune Disease
Niki Spahich, PhD
| Jul 10, 2023
| 3 min read
By editing a mutated immune regulatory gene in patient cells, Rosa Bacchetta brings hope to those suffering from IPEX syndrome.
Turning on the Bat Signal
Hannah Thomasy, PhD
| Mar 15, 2024
| 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
Which Gene Therapy Delivery Vector Will Emerge Victorious?
Danielle Gerhard, PhD
| Oct 2, 2023
| 2 min read
In the race to deliver successful gene therapies, frontrunner AAVs come head to head with underdog lipid nanoparticles.
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