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tag gene therapy developmental biology neuroscience

Image of cochlear implant and hearing aid.
Reversing Hearing Loss
Laura Tran, PhD | Nov 1, 2023 | 2 min read
Gene reactivation restored hearing after loss in mice, but the timing of intervention is key.
Using Brain Organoids in Human Health and Disease Research
Using Brain Organoids in Human Health and Disease Research
The Scientist | Jan 17, 2024 | 1 min read
Learn how scientists across life science and engineering disciplines join forces to build brain organoids that mimic neurodevelopment.
Microscopy image of a fluorescent green oligodendrocyte surrounded by astrocytes stained red with blue nuclei.
Searching for a Direct Route to Multiple Sclerosis Treatment
Deanna MacNeil, PhD | Jul 17, 2023 | 3 min read
Researchers created a new high-throughput tool to hunt for therapies that remyelinate the nervous system.
A mutated cell with a spiky membrane
Mutations in Autism-Linked Gene Cause Membrane Mischief
Holly Barker, PhD, Spectrum | Jan 26, 2023 | 4 min read
Inactivating TAOK1 prompts tentacle-like protrusions to form all over a neuron’s surface, revealing the gene’s role in molding the membrane.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.
More Autism Genes Identified
Ashley Yeager | Oct 17, 2018 | 2 min read
Researchers parse genes linked with intellectual disability and autism from those tied to autism alone.
Reprogrammed Müller Glia Restore Vision in Mice
Ashley Yeager | Aug 15, 2018 | 4 min read
A double gene-transfer therapy transformed the non-neuronal cells into rod photoreceptors in the retinas of animal models of congenital blindness.
smiling woman with hands on hips with blackboard in background
In Deep Water With Gül Dölen
Peter Hess, Spectrum | Aug 4, 2022 | 10 min read
A researcher’s existential crisis led to a scientific breakthrough.

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