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The Scientist

» gene therapy and developmental biology

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image: Messing with HIV

Messing with HIV

By | June 1, 2012

Sangamo Biosciences is putting a different spin on gene therapy. 

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image: Targeting DNA

Targeting DNA

By | June 1, 2012

After 20 years of high-profile failure, gene therapy is finally well on its way to clinical approval.

13 Comments

image: Loss of Microtubule Regulator Blocks Sperm Maturation

Loss of Microtubule Regulator Blocks Sperm Maturation

By | May 24, 2012

New research suggests that controlling cytoskeletal dynamics in sperm accessory cells may help regulate male fertility.

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image: Gene Therapy for Brain Disease

Gene Therapy for Brain Disease

By | May 16, 2012

Delivering a missing enzyme to the brains of paralyzed children with a rare, life-threatening neurological disease restores movement and builds muscle mass.

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image: Doubled Gene Boosted Brain Power

Doubled Gene Boosted Brain Power

By | May 7, 2012

Human-specific duplications of a gene involved in brain development may have contributed to our species’ unique intelligence.

6 Comments

image: Stem Cell Suicide Switch

Stem Cell Suicide Switch

By | May 3, 2012

Human embryonic stem cells swiftly kill themselves in response to DNA damage.

10 Comments

image: The Sugar Lnc

The Sugar Lnc

By | May 1, 2012

Genes that react to cellular sugar content are regulated by a long non-coding RNA via an unexpected mechanism

2 Comments

image: Boyle’s Monsters, 1665

Boyle’s Monsters, 1665

By | May 1, 2012

From accounts of deformed animals to scratch-and-sniff technology, Robert Boyle's early contributions to the Royal Society of London were prolific and wide ranging.

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image: The Two Faces of Metastasis

The Two Faces of Metastasis

By | April 1, 2012

During development, the cells of an embryo change their pattern of gene expression, which allows them to detach from their original location and migrate to another part of the embryo, where the pattern changes again to allow formation of a new organ.

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image: Are Cancer Stem Cells Ready for Prime Time?

Are Cancer Stem Cells Ready for Prime Time?

By | April 1, 2012

A flood of new discoveries has refined our definition of cancer stem cells. Now it’s up to human clinical trials to test if they can make a difference in patients.

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