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The Scientist

» gene therapy and developmental biology

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image: Celladon Shutters Its R&D

Celladon Shutters Its R&D

By | June 26, 2015

Biotech firm likely to pull the plug after its gene therapy product fails.

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image: Sperm From Ovaries

Sperm From Ovaries

By | June 11, 2015

With the deletion of a single gene, female Japanese rice fish can produce sperm. 

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image: Dino Snouts from Chicken Beaks

Dino Snouts from Chicken Beaks

By | May 13, 2015

Researchers tweak gene expression in chicken embryos that may have been crucial to the evolutionary transition from dinosaur noses to bird bills.

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image: Restored Sight Fades After Gene Therapy

Restored Sight Fades After Gene Therapy

By | May 5, 2015

Participants of two gene-therapy trials who experienced partial restoration of sight following treatment are now losing their vision once again.

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image: Viral Protector

Viral Protector

By | April 21, 2015

A retrovirus embedded in the human genome may help protect embryos from other viruses, and influence fetal development.

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image: Protein Spurs T-Cell Proliferation

Protein Spurs T-Cell Proliferation

By | April 17, 2015

A newly discovered protein promotes immunity to viruses and cancer by triggering the production of cytotoxic T cells.

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image: Contributors

Contributors

By | April 1, 2015

Meet some of the people featured in the April 2015 issue of The Scientist.

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image: From Many, One

From Many, One

By | April 1, 2015

Diverse mammals, including humans, have been found to carry distinct genomes in their cells. What does such genetic chimerism mean for health and disease?

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image: Short, Strong Signals

Short, Strong Signals

By | March 25, 2015

Methylation increases both the activity and instability of the signaling protein Notch.

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image: Reducing Gene Therapy-Related Risk

Reducing Gene Therapy-Related Risk

By | January 22, 2015

In a mouse model of a rare disease, scientists have figured out how to reduce the elevated cancer risk tied to a gene therapy treatment.

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