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tag probe immunology

Probing Protein Interactions
Laura Defrancesco | Apr 14, 2002 | 8 min read
The challenge of proteomics is personified in the Greek god, Proteus. The keeper of all knowledge, past, present and future, Proteus would not give up any information easily; even while held down, he would struggle and assume different forms before giving anything up. Remarkably, proteomics, and proteins for that matter, were not named after Proteus, but the imagery could not be more fitting. It's still anyone's guess what the final gene count will be in the human genome, let alone the total nu
Nonradioactive Probes Protect Scientists And Environment
Holly Ahern | Apr 29, 1990 | 5 min read
For many years, geneticists determined the genetic makeup of organisms by examining the physical characteristics of their offspring. But with the discovery of the structure of the DNA double helix, first published by James D. Watson and Francis H.C. Crick in 1953 (Nature, 171:964-7), the science of genetics was forever changed. Scientists soon developed techniques to study the genetic message found in all living cells at the molecular level. One of most important of these methods was the use of
The Brain’s Immune Cells Stand Sentinel Against Viral Invasion
Ashley Yeager | Oct 1, 2020 | 4 min read
Some viruses, possibly even SARS-CoV-2, can sneak into the brain through the nose. Recent studies show that microglia are ready for them when they do.
Pinpointing the Culprit
Rachel Berkowitz | Jun 1, 2017 | 8 min read
Identifying immune cell subsets with CyTOF
Molecular Multitasking
Carina Storrs | Aug 1, 2013 | 6 min read
Commercial kits use fluorescent beads to probe dozens of cytokines in one reaction.
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky | Mar 1, 2018 | 10+ min read
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
Top 10 Innovations 2013
The Scientist | Dec 1, 2013 | 10+ min read
The Scientist’s annual competition uncovered a bonanza of interesting technologies that made their way onto the market and into labs this year.
No Mo’ Slow Flow
Jeffrey M. Perkel | Jan 1, 2012 | 7 min read
Tools and tricks for high-throughput flow cytometry
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Immune cell memory tracked
Victoria Stern | Oct 25, 2009 | 3 min read
A type of antibody long thought to have a minor role in immune system memory may actually be a key player, new findings suggest. Researchers tracked the antibody's function by imaging the immune system's B cells in the act of responding to a pathogen and developing into memory B cells, which can recognize an infectious agent years after first encountering it, they report in a study published online yesterday (October 25) in Nature Immunology. B cell and memory B cell reacting to a virus Image:

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