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image: Cancer Kismet

Cancer Kismet

By | April 1, 2015

Fate mapping allows researchers to follow cancer progression from its cell type of origin.

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image: Contributors

Contributors

By | April 1, 2015

Meet some of the people featured in the April 2015 issue of The Scientist.

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image: Control ALT, Delete Cancer

Control ALT, Delete Cancer

By , and | April 1, 2015

Treating cancer by shutting down the alternative lengthening of telomeres (ALT) pathway

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image: Getting Your Sugar Fix

Getting Your Sugar Fix

By | April 1, 2015

A guide to glycan microarrays

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image: Setbacks and Great Leaps

Setbacks and Great Leaps

By | April 1, 2015

The tale of p53, a widely studied tumor suppressor gene, illustrates the inventiveness of researchers who turn mishaps into discoveries.

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image: Signaling Resistance

Signaling Resistance

By | April 1, 2015

Activating signaling pathways, rather than individual genes, reveals roles for both growth and dedifferentiation in establishing resistance to cancer treatments.

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image: Through a Spider’s Eyes

Through a Spider’s Eyes

By | April 1, 2015

Deciphering how a jumping spider sees the world and processes visual information may yield insights into long-standing robotics problems.

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image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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image: Yvonne Saenger: Immunotherapy Pioneer

Yvonne Saenger: Immunotherapy Pioneer

By | April 1, 2015

Assistant Professor, Department of Medicine, Columbia University. Age: 41

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image: From Many, One

From Many, One

By | April 1, 2015

Diverse mammals, including humans, have been found to carry distinct genomes in their cells. What does such genetic chimerism mean for health and disease?

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