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illustration of inside of human chest with highlighted gland between the lungs
Genetically Altered Mice Harness Benefits of Calorie Restriction  
A study identifies a gene that appears to be partially responsible for the health effects of a limited diet.
Genetically Altered Mice Harness Benefits of Calorie Restriction  
Genetically Altered Mice Harness Benefits of Calorie Restriction  

A study identifies a gene that appears to be partially responsible for the health effects of a limited diet.

A study identifies a gene that appears to be partially responsible for the health effects of a limited diet.

T cell

Salmonella (pink) invading a human epithelial cell (yellow)
Modified Salmonella Revs Immune Response, Combats Tumors in Mice
Natalia Mesa, PhD | Feb 3, 2022 | 5 min read
When coated with positively charged particles, the bacteria shuttled antigens out of tumors and activated the immune system, a study finds.
knitted pink heart with a mended hole
CAR T Cells Mend Broken Mouse Hearts
Sophie Fessl, PhD | Jan 6, 2022 | 4 min read
Specialized immune cells generated in vivo reduce cardiac scar tissue in mice, a new study shows.
Overcoming T Cell Therapy Barriers with Engineered Proteins
Overcoming T Cell Therapy Barriers with Engineered Proteins
The Scientist | 1 min read
Shannon Oda will discuss how to develop novel engineered fusion proteins to improve T cell therapies against hematological and solid tumors.
orange and blue cell image
Woman’s Body Appears to Rid Itself of HIV
Chloe Tenn | Nov 18, 2021 | 3 min read
Researchers report what appears to be the second case of a person’s immune system clearing the virus on its own.
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Training Immune Cells to Be Cancer Killers
Aparna Nathan, PhD | Nov 12, 2021 | 4 min read
A career-altering experience as a cancer patient motivated one researcher to design more potent immunotherapies.
The Epigenetic Landscape During T Cell Exhaustion
The Epigenetic Landscape During T Cell Exhaustion
The Scientist and 10x Genomics | 1 min read
In this webinar, E. John Wherry and Debattama Sen will discuss how epigenetic scarring of exhausted T cells influences chronic infections.
illustration of people of different genders and races
Does Biological Sex Influence COVID-19 Outcomes?
Annie Melchor | Nov 2, 2021 | 10 min read
It’s unclear whether differing odds of dying between men and women reflect inherent differences between male and female immune systems or differences rooted in gender norms.
Illustration of the BCG vaccine and resulting immune response
Infographic: TB Vaccines in the Pipeline Take Varied Approaches
Anthony King | Jul 1, 2021 | 3 min read
More than a dozen vaccines for tuberculosis are currently being tested in clinical trials. Some use whole bacteria as BCG does, while others deliver protein subunits or genetic material carried by viral vectors.  
The Many Facets of T Cell Exhaustion
The Many Facets of T Cell Exhaustion
The Scientist Creative Services Team in Collaboration with IsoPlexis | 1 min read
In this webinar, Abhishek Garg will discuss using functional proteomics and multi-omics approaches to explore exhausted/dysfunctional T cell states in various cancers.
False-colored micrograph of Mycobacterium tuberculosis
Tuberculosis: The Forgotten Pandemic
Anthony King | Jul 1, 2021 | 10+ min read
This month marks the 100-year anniversary of BCG, still the only approved vaccine against the lethal pathogen. But there are new vaccines for this wily foe on the horizon.
A scanning electron micrograph of a fetal gut, pseudocolored in yellow and blue
Microbes in Human Fetuses Spur Immune Development
Abby Olena, PhD | Jun 3, 2021 | 4 min read
Researchers identify live bacteria in fetal guts, skin, lungs, and placentas that activate memory T cells, indicating that early exposure to microbes could help educate the developing immune system.
A Spotlight on T Cell Exhaustion
A Spotlight on T Cell Exhaustion
The Scientist | 1 min read
Mary Philip and Benjamin Youngblood discuss how T cell exhaustion affects cancer progression and immunotherapy efficacy.
Mucosal Vaccines Protect Mice from Viruses, Cancer
Emma Yasinski | Jun 1, 2021 | 2 min read
Scientists use a protein found in mucus membranes to ferry vaccines to the lymph nodes.
US and Chinese flags
Ohio State Researcher Sentenced to Prison for Secret China Ties
Lisa Winter | May 17, 2021 | 2 min read
Rheumatologist Song Guo Zheng pleaded guilty in November to delivering US-funded research to China.
Cancer Vaccines: Raising a T Cell Army
Niki Spahich, PhD | 1 min read
Vaccines against various forms of cancer prime the immune system to attack.
cancer blood hematologic leukemia solid tumor covid-19 sars-cov-2 coronavirus pandemic mortality t cell b cd8+ cd4+ immunology chemotherapy
COVID-19 More Deadly with Blood than Solid Cancer: Study
Marcus A. Banks | Feb 16, 2021 | 4 min read
Death rates among blood cancer patients who contract COVID-19 are higher than for those with other cancers, pointing to impaired immunity that makes it hard to overcome the virus.
Common Cold Coronaviruses Tied to Less Severe COVID-19 Cases
Anthony King | Nov 11, 2020 | 5 min read
Outcomes in COVID-19 patients may be better in those recently infected with endemic coronaviruses. 
Checking Checkpoints for Treating Cancer
The Scientist | 1 min read
Researchers devise strategies to improve checkpoint inhibitor therapy and predict patient response.
Doctors Consider Convalescent T Cell Therapy for COVID-19
Abby Olena, PhD | Nov 6, 2020 | 3 min read
Researchers propose that an infusion of memory T cells from people who have recovered from SARS-CoV-2 infections could treat severe disease.
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