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tag b cell genetics genomics

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
B cells secreting antibodies that target virus particles.
Stem Cell Editing Repairs Severe Immunodeficiency
Kamal Nahas, PhD | Mar 20, 2024 | 5 min read
Scientists hoping to treat immunodeficiencies using gene therapy have found a way to edit stem cells in mice without disrupting gene regulation.
All Roads Lead to Genome Editing
Danielle Gerhard, PhD | Feb 9, 2024 | 6 min read
Shondra Pruett-Miller has taken many paths in her career with her love of genome editing always as a guiding light.
Researchers can obtain epigenetic information in addition to genetic insights from a single DNA sample.
The Six-Base Genome Reveals Multimodal Data from a Single DNA Sample
The Scientist and biomodal | Mar 12, 2024 | 4 min read
To gather multiomic insights, researchers used to combine data from multiple workflows, but duet evoC provides more information from less sample in one workflow.
MULTI-seq: Single-Cell Genomic Sample Multiplexing Using Lipid-Tagged Indices
MULTI-seq: Single-Cell Genomic Sample Multiplexing Using Lipid-Tagged Indices
The Scientist | May 9, 2022 | 1 min read
In this webinar, Chris McGinnis and Jennifer Silverman discuss how MULTI-seq offers improved sample throughput and data quality.
Individual bacterial transcriptomes each plotted as a single point create a ring-shaped structure.
Rapidly Dividing Bacteria Coordinate Gene Expression and Replication
Kamal Nahas, PhD | Mar 15, 2024 | 4 min read
E. coli divides faster than it can replicate its genome, while simultaneously expressing its genes. Scientists recently revealed the intricate molecular coordination that makes this possible.
A person moving the hands of a vintage clock backwards.
Synthetic Circuits Reveal the Key to Rewinding the Cellular Clock
Charlene Lancaster, PhD | Mar 12, 2024 | 4 min read
Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.
Bio-Rad Launches Vericheck ddPCR Replication Competent Lentivirus and Replication Competent AAV Kits for Cell and Gene Therapy Production
Bio-Rad Laboratories | Feb 27, 2024 | 2 min read
Rapid, Sensitive, and Validated Detection of Viral Replication Genes Using Droplet Digital™ PCR During Cell and Gene Therapy Production
Yeast Made to Harvest Light Hint at Evolution’s Past
Kamal Nahas, PhD | Feb 21, 2024 | 6 min read
Scientists transferred light-harvesting proteins into yeast for the first time, shining a light on the past lives of eukaryotic cells.
Glass mosaic with the image of two people. The bodies are arbitrarily crossed by lines that divide them into amorphous fractions, some of them colored.
Noninherited Genetic Mutations Link to Schizophrenia
Alejandra Manjarrez, PhD | Jul 20, 2023 | 2 min read
By studying the genomes of more than 24,000 individuals, researchers discovered rare genetic mutations that may shed light on mechanisms underlying schizophrenia.

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