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tag mhc molecules immunology

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Cancer Vaccination as a Promising New Treatment Against Tumors
Shelby Bradford, PhD | Mar 15, 2024 | 10+ min read
Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.
Immunology
The Scientist Staff | Apr 2, 1995 | 2 min read
Edited by: Neeraja D. Sankaran R.M. Chicz, R.G. Urban, J.C. Gorga, D.A.A. Vignali, W.S. Lane, J.L. Strominger, "Specificity and promiscuity among naturally processed peptides bound to HLA-Dr alleles," Journal of Experimental Medicine, 178:27-47, 1993. (Cited in 107 publications through January 1995) Comments by Roman M. Chicz,department of molecular and cellular biology, Harvard University One of the most important findings in this article, according to its authors, was the observation of pr
Histology of mouse lungs using purple and green staining on a white background. Left: a healthy lung. Right: a fibrotic lung.<br><br>
Immunotherapy Treats Fibrosis in Mice
Alejandra Manjarrez, PhD | Sep 15, 2022 | 4 min read
Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.
Pinpointing the Culprit
Rachel Berkowitz | Jun 1, 2017 | 8 min read
Identifying immune cell subsets with CyTOF
The Jon Yewdell Selection
Jon Yewdell | Apr 6, 2003 | 3 min read
My Top 5 | The Jon Yewdell Selection Courtesy of Jon Yewdell 1. In the now distant year of 1970, the physical nature of the plasma membrane (or any membrane for that matter) was uncertain. Frye and Edidin used Sendai virus to fuse human and mouse cell, then stained the cells with fluorochrome-labeled antibodies specific for human or mouse antigens.1 They watched the unfolding drama in a fluorescent microscope as the human and mouse proteins completely mixed in real time, providing an elega
Human Clinical Trials Begin For Cervical Cancer Vaccines
Steve Bunk | Oct 26, 1997 | 6 min read
Efforts are under way to develop a vaccine against one of the world's deadliest illnesses, cervical cancer. Along with a number of university research laboratories, at least a half-dozen biotechnology and pharmaceutical companies are beginning clinical trials or are in preclinical development of such drugs. Efficacy in humans remains to be firmly established, but if the vaccines progress to later-phase trials, challenging jobs for immunologists, microbiologists, and biochemists will multiply. "
Cell-Signaling A Cascade of Kinases, Phosphatases, and Cytokines
Deborah Noble | Jul 4, 1999 | 8 min read
Date: July 5, 1999Table of Cell Signaling Tools At today's research pace, new signaling mechanisms within and between cells are emerging not one by one but in a chain reaction. Each new discovery has strong implications for previously established models, sometimes overturning several assumptions at once. With such a large number of interacting systems--from cell adhesion to differentiation and apoptosis--and receptor pathways, keeping up with the wealth of cell-signaling research tools can be l

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