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Measuring PD-L1 levels was a great start. Now we need to quantify more protein biomarkers, assess the tumor mutational landscape, and examine immune cell signatures, too.

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image: Circadian Rhythms Influence Treatment Effects

Circadian Rhythms Influence Treatment Effects

By | April 1, 2017

Across many diseases, taking medication at specific times of day may make the therapy more effective.

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image: Infographic: Circadian Clock Affects Health and Disease

Infographic: Circadian Clock Affects Health and Disease

By | April 1, 2017

The body's rhythms could affect numerous ailments as well as how people respond to treatments.

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image: Should Healthy People Have Their Exomes Sequenced?

Should Healthy People Have Their Exomes Sequenced?

By | March 24, 2017

With its announced launch of a whole-exome sequencing service for apparently healthy individuals, Ambry Genetics is the latest company to enter this growing market. But whether these services are useful for most people remains up for debate.  

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image: Pathway to Polio Virulence Revealed

Pathway to Polio Virulence Revealed

By | March 23, 2017

Using epidemiological and laboratory data, scientists have mapped out a sequence of mutations through which the attenuated oral polio vaccine reverts to a virulent virus.

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Scientists issue a call to reconsider the rules governing the creation of tissues, organs, and other structures made possible by recent advances in synthetic biology. 

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image: San People Write Ethical Code for Research

San People Write Ethical Code for Research

By | March 21, 2017

With lifestyles similar to our hunter-gatherer ancestors, the San people of Southern Africa are popular study subjects.

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image: U.K. Moves Forward With Three-Parent IVF

U.K. Moves Forward With Three-Parent IVF

By | March 20, 2017

The country’s fertility regulator has approved the first application to carry out mitochondrial replacement therapy, which uses biological material from two women and one man to create an embryo.

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image: Singing Through Tone Deafness

Singing Through Tone Deafness

By | March 17, 2017

Author Tim Falconer didn't take his congenital amusia lying down. With the help of neuroscientists and vocal coaches, he tried to teach himself to sing against all odds.

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image: Inflammation Drives Gut Bacteria Evolution

Inflammation Drives Gut Bacteria Evolution

By | March 16, 2017

Viruses within Salmonella rapidly spread genes throughout the bacterial population during a gut infection, scientists show.

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