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Contributors

By | January 1, 2017

Meet some of the people featured in the January 2017 issue of The Scientist.

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image: Pharma Redo

Pharma Redo

By | January 1, 2017

Steve Braun of Cures Within Reach, a nonprofit focused on breathing new life into old medicines, describes the potential benefits of drug repurposing.

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Oncologists have raised concerns about a mouse study that suggests the vaccine for human papillomavirus could cause brain damage.

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image: Top Technical Advances 2016

Top Technical Advances 2016

By | December 15, 2016

The year’s most impressive achievements include methods to watch translation in cells, trace cell fates, avoid mitochondrial mutations, edit DNA, and build antibiotics from scratch.

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image: Oligonucleotide Therapeutics Near Approval

Oligonucleotide Therapeutics Near Approval

By | December 1, 2016

Successful late-stage clinical trials could mark the maturation of a new drug development platform, but the path to commercialization is not without hurdles.

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image: Synthetic Sensors

Synthetic Sensors

By | December 1, 2016

Engineered circuits detect endogenous transcription factors to drive cellular outputs.

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image: Infographic: How to Build a Synthetic Sensor

Infographic: How to Build a Synthetic Sensor

By | December 1, 2016

Scientists designed a genetic sensor-and-readout system, based on detecting a transcription factor, that performs a custom cellular activity.

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Researchers are using the tissue, synthesized with human pluripotent stem cells and implanted into mice, to study a rare form of Hirschprung’s disease.

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image: More Success Fixing Sickle Cell Gene with CRISPR

More Success Fixing Sickle Cell Gene with CRISPR

By | November 9, 2016

Researchers say they have sufficient in vitro and animal data to apply for human testing.

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Family members with a certain gene variant had unnecessary interventions, highlighting the potential hazards of precision medicine.

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