Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 

Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.

Blocking an abnormally active signaling pathway in skeletal stem and progenitor cells alleviates bone mass decline in middle-aged mice. 

The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.

A.D. Friedman, W.H. Landschulz, S.L. McKnight, "CCAAT/enhancer binding protein activates the promoter of the serum albumin gene in cultured hepatoma cells," Genes & Development, 3: 1314-22, 1989. Alan D. Friedman (Johns Hopkins Oncology Center, Baltimore): "CCAAT/enhancer binding protein (C/EBP) is perhaps best known as the prototypical basic region-leucine zipper DNA-binding protein (Science, 243:1681-88, 1989). This paper, however, represents part of the earliest efforts of the McKnight labo

M.P. Kamps, C. Murre, X.-h. Sun, D. Baltimore, "A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in Pre-B ALL," Cell, 60:547- 55, 1990. Mark Kamps (University of California, San Diego): "In man, most chromosomal translocations elicit tumorigenic effects by introducing a strong enhancer adjacent to a normal cellular gene, such as c-MYC, and constitutively activating its expression. Less frequently, a chimeric oncogene forms by the joining of two distinc

Beyond The Scientist’s coverage of COVID-19’s molecular underpinnings were many other stories highlighting the advances made in scientists’ understanding of the biology of cells.