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image: Finding Enhancers with CRISPR

Finding Enhancers with CRISPR

By | January 11, 2016

Researchers use CRISPR/Cas9 to screen for noncoding elements in the human genome.


image: Silencing Surprise

Silencing Surprise

By | June 1, 2015

A chromatin remodeler in embryonic stem cells clears the DNA for mRNA transcription while stifling the expression of noncoding transcripts.


image: Bigger Brains

Bigger Brains

By | February 20, 2015

Researchers identify a human DNA element that spurs neurogenesis and brain growth when placed in mice.

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image: DNA Loop-the-Loops

DNA Loop-the-Loops

By | December 11, 2014

A new full-genome map indicates how DNA is folded within the nuclei of human cells.


image: Enhanced Enhancers

Enhanced Enhancers

By | November 1, 2014

The recent discovery of super-enhancers may offer new drug targets for a range of diseases.


image: Exploring the Roles of Enhancer RNAs

Exploring the Roles of Enhancer RNAs

By | May 7, 2014

Scientists have recently discovered that enhancers are often transcribed into RNAs. But they’re still not sure what, if anything, these eRNAs do.

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image: Enhancer and Promoter Atlases

Enhancer and Promoter Atlases

By | March 26, 2014

Consortium annotates the human genome with cell type-specific information about transcription start sites, active enhancers, and their expression throughout the body.


image: About Face

About Face

By | October 25, 2013

Researchers show that genetic enhancer elements likely contribute to face shape in mice.


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