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tag pain evolution cell molecular biology

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
How Evolution Made the Highveld Mole Rat Impervious to Ant Stings
Shawna Williams | Sep 1, 2019 | 5 min read
Researchers identify changes to a pain receptor and to an ion channel that appear to enable the rodents to colonize otherwise inhospitable burrows.
Senior woman wearing a grey pullover sitting on a bed and holding her back.
Early Inflammation Protects Against Chronic Pain, Study Finds
Alejandra Manjarrez, PhD | May 12, 2022 | 3 min read
Human data and experiments in mice challenge the common use of anti-inflammatory drugs to treat pain.
Tag, You're It
Carina Storrs | Feb 1, 2014 | 7 min read
A guide to DNA-encoded libraries for drug discovery
Image of someone scratching their skin.
A Chronic Itch: Burrowing Beneath the Skin
Brian S. Kim, MD | Sep 8, 2023 | 9 min read
We have barely scratched the surface of itch science and what it indicates about our health.
Top 7 papers in cell biology
Jef Akst | Dec 5, 2010 | 3 min read
Just in time for ASCB -- see the cell biology articles most highly ranked by F1000
An Offensive Playbook
Mary Beth Aberlin | Feb 1, 2014 | 3 min read
Developing nonaddictive drugs to combat pain
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Artist’s rendition of a blue-green DNA double helix, viewed lengthwise from within one end.
Stem Cell Lines Riddled With Undetected Mutations
Dan Robitzski | Aug 12, 2022 | 4 min read
Most of the human induced pluripotent stem cells stored at major cell line repositories and used in research harbor thousands of DNA errors, a study finds, highlighting the need for improved quality control measures.
The Right Sort
Richard P. Grant | Aug 1, 2011 | 3 min read
Using the strongest molecular binding partnership in biology to separate different cell types.

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