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tag surgery genetics genomics

Diagnosing Cancer: A Genomics and Proteomics Approach
Tom Hollon | Sep 21, 2003 | 7 min read
In 1996, Jeff Trent and colleagues published the first paper describing DNA microarrays as tools for pinpointing gene variants underlying various tumor properties.1 Now, as president and scientific director of Translational Genomics Research Institute (TGEN), in Phoenix, Trent is using microarrays to look for gene expression patterns that can be applied to developing diagnostics. The role of microarrays, Trent says, "will be on the discovery side. Testing all 30,000 genes against a diagnosti
The Rodent Wars: Is a Rat Just a Big Mouse?
Ricki Lewis | Jul 4, 1999 | 5 min read
Sometimes it seems as if genome projects are cropping up everywhere.1 But until costs come down, limited resources are being largely concentrated into what Joseph Nadeau, professor of genetics at Case Western Reserve University School of Medicine, calls "the genome seven," an apples-and-oranges list of viruses, bacteria, fungi, Arabidopsis thaliana, Drosophila melanogaster, Caenorhabditis elegans, and mouse, with Homo sapiens in its own category.2 Researchers widely acknowledge that in the rod
Notebook
The Scientist Staff | Sep 1, 1997 | 7 min read
Table of Contents More Newsworthy Sheep Grade Strike Earns an F Brain Drain Sexual Chemistry Cheaper Journals Michign Misconduct Matters Lucky 7 Cloning BRCA2 Credit: Graham G. Ramsay ON THE LAMB: Dario Fauza performed fetal surgery on ovine patients. While Dolly the cloned sheep has yet to disappear from the headlines, other ovines have made medical history. Dario Fauza, a fellow at Harvard Medical School and Children's Hospital in Boston, along with Anthony Atala, an assistant professor of
Those We Lost in 2018
Ashley Yeager | Dec 26, 2018 | 10+ min read
The scientific community said goodbye to a number of leading researchers this year.
Innovations Expand Lab Power, Uses Of PCR Technique
Ricki Lewis | Jul 25, 1993 | 8 min read
The gene amplification technique invented by genetics researcher Kary Mullis on a moonlit drive through the northern California hills a decade ago--the polymerase chain reaction (PCR)-- continues to revolutionize the life sciences. Uses in molecular biology research and in diagnostic tests are proliferating, and PCR is even bringing a new molecular approach to such fields as paleontology and epidemiology. The following companies are among those supplying PCR-related products for the resear
Brains in Action
The Scientist | Feb 1, 2014 | 10+ min read
Neuroscientists are automating neural imaging and recording, allowing them to monitor increasingly large swaths of the brain in living, behaving animals.
 
My Mighty Mouse
Megan Scudellari | Apr 1, 2015 | 10+ min read
Personal drug regimens based on xenograft mice harboring a single patient’s tumor still need to prove their true utility in medicine.
Top Ten Innovations 2010
Megan Scudellari | Dec 1, 2010 | 10+ min read
By The Scientist Staff Top Ten Innovations 2010 Innovative products that have the life science community buzzing. As the global economy continues to pull out of its recent precipitous nosedive, one mantra rings true from Beijing to Boston—innovation can save us. If developing interesting new technologies and products really is the lifeblood of economic health, then the life sciences industry is innovation’s beating heart. The Scientist rec
How Well Do Mice Model Humans?
Ricki Lewis | Oct 25, 1998 | 8 min read
STRIKING RESEMBLANCE: James Croom, who studies Down syndrome mice at North Carolina State University, says the animals are providing valuable information useful to humans. When a page-one article in the May 3, 1998, Sunday New York Times portrayed angiogenesis inhibitors that fight cancer in mice as being possible just around the corner for humans, criticism for raising false hopes erupted. Merely 10 weeks later, however, when researchers from the University of Hawaii reported cloning the fi
DNA Sequencing: Today's Technology And Beyond
Scott Veggeberg | Oct 16, 1994 | 10+ min read
SUPPLIERS OF DNA SEQUENCERS, SYSTEMS, AND SOFTWARE American Bioanalytical Inc. Natick, MA Circle No. 101 on Reader Service Card Amersham Corp. Arlington Heights, IL Circle No. 102 on Reader Service Card Applied Biosystems Division of Perkin-Elmer Foster City, CA Circle No. 103 on Reader Service Card Beckman Instruments Inc. Fullerton, CA Circle No. 104 on Reader Service Card Biomed Instruments Inc. Fullerton, CA Circle No. 105 o

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