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tag nematodes genetics genomics

Top 7 in Genomics & Genetics
Bob Grant | Jul 19, 2011 | 3 min read
A snapshot of the most highly ranked articles in genomics, genetics, and related areas, from Faculty of 1000
Mitochondrial Isolation System
Ruth Williams | May 1, 2018 | 3 min read
A transgenic approach allows researchers to collect the organelles from specific cells in nematodes with unprecedented efficiency.
Long live the worm!
Jeff Perkel | Jun 29, 2005 | 1 min read
In tomorrow's (July 1) issue of Genes & Development, Siu Sylvia Lee, of the department of molecular biology and genetics at Cornell University in Ithaca, NY, and Gary Ruvkun, of the department of genetics at Harvard Medical School, report ?the first genome-wide functional genomic screen for longevity genes.? The two teams used a library of 16,475 RNA interference constructs (created by Julie Ahringer at the University of Cambridge, UK) to inactivate genes in the nematode, Caenorhabditis eleg
The Genetics of Society
Claire Asher and Seirian Sumner | Jan 1, 2015 | 10 min read
Researchers aim to unravel the molecular mechanisms by which a single genotype gives rise to diverse castes in eusocial organisms.
Genome Economy
Ricki Lewis | Jun 10, 2001 | 10 min read
The Human Genome Project's discovery1 that the human body runs on an instruction manual of a mere 35,000 or so genes--compared to the worm's 19,000, the fruit fly's 13,000, and the tiny mustard relative Arabidopsis thaliana's 25,000--placed humanity on an even playing field with these other, supposedly simpler, organisms. It was a humbling experience, but humility quickly gave way to awe with the realization that the human genome might encode 100,000 to 200,000 proteins. Scientists base this num
Photo of Junyue Cao
Junyue Cao Applies Novel Approaches to Aging and Disease
Lisa Winter | Mar 14, 2022 | 3 min read
The Rockefeller University geneticist is tracing the full lifespan of individual cells to better understand how and why humans age.
Trickle-Down Genomics: Reforming ""Small Science"" As We Know It
Edward Smith | Jul 18, 1999 | 7 min read
if (n == null) The Scientist - Trickle-Down Genomics: Reforming ""Small Science"" As We Know It The Scientist 13[15]:19, Jul. 19, 1999 Opinion Trickle-Down Genomics: Reforming "Small Science" As We Know It By Edward J. Smith Each generation attempts to develop programs and activities that help it fulfill the ancient Chinese wish "May you live in interesting times." These are indeed interesting times from the perspective of the biologist: The complete geno
Yeast: An Attractive, Yet Simple Model
Gregory Smutzer | Sep 16, 2001 | 9 min read
Yeast possesses many characteristics that make it especially useful as a model system in the laboratory, including an entirely sequenced genome. Recently, a number of researchers published studies detailing the transition from genome sequencing to functional genomics. Notably, these scientists have developed new high-throughput approaches to the characterization of large numbers of yeast genes. In aggregate, these studies make yeast one of the most well-characterized eukaryotic organisms known.
Those We Lost in 2018
Ashley Yeager | Dec 26, 2018 | 10+ min read
The scientific community said goodbye to a number of leading researchers this year.
Probing Protein Interactions
Laura Defrancesco | Apr 14, 2002 | 8 min read
The challenge of proteomics is personified in the Greek god, Proteus. The keeper of all knowledge, past, present and future, Proteus would not give up any information easily; even while held down, he would struggle and assume different forms before giving anything up. Remarkably, proteomics, and proteins for that matter, were not named after Proteus, but the imagery could not be more fitting. It's still anyone's guess what the final gene count will be in the human genome, let alone the total nu

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