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tag circadian clocks genetics genomics

Newborn baby rats lie in a basket
Mother’s Circadian Rhythms Mirrored in Fetal Rat Brains
Bianca Nogrady | Sep 12, 2022 | 2 min read
Before their own central clocks develop, the brains of fetal rats detect their mother’s metabolic cycle to help regulate the expression of certain genes.
A Nile rat sitting atop fruits
Genome Spotlight: Nile Rat (Avicanthis niloticus)
Christie Wilcox, PhD | Nov 23, 2022 | 4 min read
A reference sequence for this emerging model organism will facilitate research on type 2 diabetes and the health effects of circadian rhythm disruption.
An Aging-Related Effect on the Circadian Clock
Anna Azvolinsky | Feb 21, 2017 | 3 min read
Stress-related genes may be preferentially and rhythmically expressed as part of the circadian rhythms of older fruit flies, researchers report.  
Circadian Clock Genes Help a Crop Pest Adapt to Climate Change
Emily Makowski | Jan 13, 2020 | 3 min read
As global temperatures rise and winters shorten, caterpillars of the corn borer moth are emerging earlier in parts of the US thanks to changes in two genes, researchers find.
Retinal clock regulates vision
Melissa Lee Phillips | Aug 22, 2007 | 3 min read
A clock in the mammalian retina controls visual processing independent of "master" circadian clock
Retinal clock regulates vision
Melissa Lee Phillips | Aug 22, 2007 | 3 min read
A clock specific to the mammalian retina controls visual processing independent of the "master" circadian clock
Circadian Rhythm Homology and Divergence
Eugene Russo | Jul 9, 2000 | 7 min read
Courtesy of ScienceThe fruit fly circadian cycle shares three strong similarities with the mammalian: the per gene itself, CLOCK and BMAL regulation of per, and a gene called tau in hamsters and double-time (dbt) in flies, both of which encode the enzyme CKI*. Molecular biologists have been teasing apart the intricate innards of organisms' biological clocks for decades, gaining rare insight into a veritable bridge between genes and behavior. Those clocks' circadian rhythms, the 24-hour cycles t
Circadian Rhythms
Eugene Russo | Oct 24, 1999 | 4 min read
D.P. King, Y.L. Zhao, A.M. Sangoram, L.D. Wilsbacher, M. Tanaka, M.P. Antoch, T.D.L. Steeves, M.H. Vitaterna, J.M. Kornhauser, P.L. Lowrey, F.W. Turek, J.S. Takahashi, "Positional cloning of the mouse circadian Clock gene," Cell, 89:641-53, May 16, 1997. (Cited in more than 160 papers since publication) Comments by Joseph S. Takahashi, a Howard Hughes Medical Institute investigator and professor of neurobiology and physiology at Northwestern University This paper proved to be as significant for
Muscle Clocks Play a Role in Regulating Metabolism
Diana Kwon | Sep 1, 2018 | 9 min read
Just 20 years ago, scientists didn’t even realize muscles had their own circadian clocks. Now they are beginning to appreciate their importance in health. 
High-Throughput Technology Tackles Circadian Rhythms
Karen Kreeger | Nov 16, 2003 | 7 min read
Like watchmakers, biologists have hunkered down over their respective model organisms, meticulously seeking out biological timekeepers, the genes important for regulating life's internal clock. Up until now, classical approaches had not uncovered the finest details of the machinery that synchronizes life processes with light and darkness, let alone how these rhythms affect behavior and metabolism. "[They] haven't identified genes other than the main components such as the central transcriptio

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