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tag cardiovascular disease developmental biology neuroscience

GWAS, psychotic disorder, mood disorder, Q&A, bipolar disorder, schizophrenia, depression, sex differences
Genetic Variants Tied to Sex Differences in Psychiatric Disorders
Amanda Heidt | Mar 31, 2021 | 5 min read
The largest study of its kind identifies single nucleotide polymorphisms with disparate effects on men’s and women’s susceptibility to conditions such as bipolar disorder and schizophrenia.
Antibody Alternatives
Paul Ko Ferrigno and Jane McLeod | Feb 1, 2016 | 10+ min read
Nucleic acid aptamers and protein scaffolds could change the way researchers study biological processes and treat disease.
Advances in the functional characterization of newly discovered microproteins hint at their diverse roles  in health and disease
The Dark Matter of the Human Proteome
Annie Rathore | Apr 1, 2019 | 10 min read
Advances in the functional characterization of newly discovered microproteins hint at diverse roles in health and disease.
2020 Top 10 Innovations
The Scientist | Dec 1, 2020 | 10+ min read
From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.
Into the Limelight
Kate Yandell | Oct 1, 2015 | 8 min read
Glial cells were once considered neurons’ supporting actors, but new methods and model organisms are revealing their true importance in brain function.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Brains in Action
The Scientist | Feb 1, 2014 | 10+ min read
Neuroscientists are automating neural imaging and recording, allowing them to monitor increasingly large swaths of the brain in living, behaving animals.
 
How Orphan Drugs Became a Highly Profitable Industry
Diana Kwon | May 1, 2018 | 10+ min read
Government incentives, advances in technology, and an army of patient advocates have spun a successful market—but abuses of the system and exorbitant prices could cause a backlash.
How the Lysophospholipid Got its Receptor
Jerold Chun | Sep 1, 2007 | 10+ min read
How the Lysophospholipid Got its Receptor The discovery of a new family of lipid receptors provides potential targets for diseases such as multiple sclerosis and autoimmunity. By Jerold Chun Related Articles 1 By the late 1960s, researchers had become aware that this somewhat obscure class of lipids had the remarkable ability to act like an extracellular signaling molecule.2 Two prominent forms typify but do not limit lysophospholipids: lysophosphatidic acid
The Connexin Connection
Harvey Black | Feb 6, 2000 | 6 min read
Biologists are vigorously and enthusiastically exploring the structure and function of channels known as connexins, which link cells to one another. Connexin research is "hot," says one scientist heavily involved in the field, as investigators seek to answer a host of questions ranging from what passes through these channels to when and why they appear and disappear. Understanding how these channels work may also lead to improved drugs for diseases linked with connexin mutations. "From my perspe

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