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Measuring PD-L1 levels was a great start. Now we need to quantify more protein biomarkers, assess the tumor mutational landscape, and examine immune cell signatures, too.

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image: Starvation Response Triggers Melanoma Invasion

Starvation Response Triggers Melanoma Invasion

By | April 1, 2017

Through similar mechanisms, amino acid depletion in culture and cytokine activity in the tumor microenvironment prompt cancer cells to metastasize.

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image: Circadian Rhythms Influence Treatment Effects

Circadian Rhythms Influence Treatment Effects

By | April 1, 2017

Across many diseases, taking medication at specific times of day may make the therapy more effective.

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image: Infographic: Circadian Clock Affects Health and Disease

Infographic: Circadian Clock Affects Health and Disease

By | April 1, 2017

The body's rhythms could affect numerous ailments as well as how people respond to treatments.

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image: Infographic: Mechanisms of Resistance

Infographic: Mechanisms of Resistance

By | April 1, 2017

Cancers appear to be able to evolve resistance to many of the therapies doctors have tried.

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image: In Certain Social Bees, Gut Microbiomes Follow Phylogeny

In Certain Social Bees, Gut Microbiomes Follow Phylogeny

By | March 29, 2017

Corbiculate bees and their gut-dwelling microbes have been coevolving since the social species evolved from their solitary ancestors around 80 million years ago, scientists suggest. 

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image: Should Healthy People Have Their Exomes Sequenced?

Should Healthy People Have Their Exomes Sequenced?

By | March 24, 2017

With its announced launch of a whole-exome sequencing service for apparently healthy individuals, Ambry Genetics is the latest company to enter this growing market. But whether these services are useful for most people remains up for debate.  

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image: Pathway to Polio Virulence Revealed

Pathway to Polio Virulence Revealed

By | March 23, 2017

Using epidemiological and laboratory data, scientists have mapped out a sequence of mutations through which the attenuated oral polio vaccine reverts to a virulent virus.

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image: San People Write Ethical Code for Research

San People Write Ethical Code for Research

By | March 21, 2017

With lifestyles similar to our hunter-gatherer ancestors, the San people of Southern Africa are popular study subjects.

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image: Singing Through Tone Deafness

Singing Through Tone Deafness

By | March 17, 2017

Author Tim Falconer didn't take his congenital amusia lying down. With the help of neuroscientists and vocal coaches, he tried to teach himself to sing against all odds.

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  1. Opinion: Why I Published in a Predatory Journal
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    My “colleagues” and I at the fictitious Arthur Vandelay Urological Research Institute were surprised to find our bogus “uromycitisis” case report swiftly accepted, with only minor revisions requested.

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