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image: Professional Marksman

Professional Marksman

By | April 1, 2015

Charles Sawyers, who began his research career just as the genetic details of human oncogenes were emerging, codeveloped Gleevec, the quintessential targeted cancer therapy.

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image: Setbacks and Great Leaps

Setbacks and Great Leaps

By | April 1, 2015

The tale of p53, a widely studied tumor suppressor gene, illustrates the inventiveness of researchers who turn mishaps into discoveries.

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image: The CAR T-Cell Race

The CAR T-Cell Race

By | April 1, 2015

Tumor-targeting T-cell therapies are generating remarkable remissions in hard-to-beat cancers—and attracting millions of dollars of investment along the way.

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image: The Challenges of Precision

The Challenges of Precision

By | April 1, 2015

Researchers face roadblocks to treating an individual patient’s cancer as a unique disease.

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image: To Each His Own

To Each His Own

By | April 1, 2015

Cancer treatment becomes more and more personal.

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image: Two-Faced RNAs

Two-Faced RNAs

By | April 1, 2015

The same microRNAs can have opposing roles in cancer.

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image: From Many, One

From Many, One

By | April 1, 2015

Diverse mammals, including humans, have been found to carry distinct genomes in their cells. What does such genetic chimerism mean for health and disease?

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image: My Mighty Mouse

My Mighty Mouse

By | April 1, 2015

Personal drug regimens based on xenograft mice harboring a single patient’s tumor still need to prove their true utility in medicine.

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image: Resisting Cancer

Resisting Cancer

By | April 1, 2015

If one out of three people develops cancer, that means two others don’t. Understanding why could lead to insights relevant to prevention and treatment.

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image: Hiding in Plain Sight

Hiding in Plain Sight

By | March 31, 2015

Researchers using metagenomics and single-cell sequencing identify a potential new bacterial phylum.

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