The device can chill nerves as small as a few millimeters across, but more testing and modifications are necessary before it could relieve pain in humans.
The National Academies’ report touches on ethical issues raised by new technologies such as brain organoids and human-animal chimeras, and suggests that current regulatory oversight is sufficient.
A study that compared several anesthetic regimens in rodents showed that only one—inhaled isoflurane—wasn’t detrimental to the activity of neurons in the hippocampus.
The largest study of its kind identifies single nucleotide polymorphisms with disparate effects on men’s and women’s susceptibility to conditions such as bipolar disorder and schizophrenia.
A physician and neurobiologist at the Rockefeller University who specialized in addiction research, Kreek was best known for her work on developing the treatment for heroin addiction.
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
Manipulating the production of new neurons can improve cognition in animal models of the disease, raising the possibility that figuring out a way for humans to make more neurons could make a difference for people with dementia.
The variant causes a buildup of BACE1 protein in axons in cultured neurons and mice. Researchers say it might be time to rethink failed trials that inhibit BACE1 to treat the neurodegenerative disease.