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image: The Challenges of Rare-Disease Research

The Challenges of Rare-Disease Research

By | September 1, 2016

With few resources and hesitant investors, basic scientists must rely on clinicians, patient advocates, and their own keen eye for biological connections.

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Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

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image: Popular Tumor Cell Line Contaminated

Popular Tumor Cell Line Contaminated

By | August 31, 2016

A commercially available glioblastoma cell line appears to be from a different source than its stated origins.

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image: One Receptor, Two Ligands, Different Responses

One Receptor, Two Ligands, Different Responses

By | August 31, 2016

Host and bacterial ligands that interact with the same cell-surface receptor induce different activities in human macrophages. 

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image: Opinion: GMOs Are Not “Frankenfoods”

Opinion: GMOs Are Not “Frankenfoods”

By and | August 30, 2016

It behooves the scientific community to reflect on the public’s “Franken-” characterization of genetically modified foods.

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The marsupials’ genomes show evidence of a rapid evolutionary response to selection imposed by devil facial tumor disease.

2 Comments

image: Newly Discovered Virus Has Multi-Part Genome

Newly Discovered Virus Has Multi-Part Genome

By | August 26, 2016

A “multicomponent” virus isolated from mosquitoes infects in stages and reassembles once the pieces are inside the host.

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image: One Antigen Receptor Induces Two T cell Types

One Antigen Receptor Induces Two T cell Types

By | August 26, 2016

Precursor T cells bearing the same antigen receptor adopt two different fates in mice.

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image: Streamlining the <em>E. coli</em> Genetic Code

Streamlining the E. coli Genetic Code

By | August 18, 2016

Scientists design a bacterial genome with only 57 codons.

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image: Exploring Alternative Codon Usage in Yeast

Exploring Alternative Codon Usage in Yeast

By | August 18, 2016

Newly discovered amino acid reassignment could have implications for certain biotech applications and RNA-based evolutionary theories.

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