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image: Fatal Disease Drug in Limbo

Fatal Disease Drug in Limbo

By | November 25, 2015

A panel of experts advised the US Food and Drug Administration that BioMarin Pharmaceutical has not demonstrated efficacy of its new drug for Duchenne muscular dystrophy.

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image: How Gastric Bypass Can Kill Sugar Cravings

How Gastric Bypass Can Kill Sugar Cravings

By | November 19, 2015

A type of bariatric surgery eliminates gut-to-brain signals that trigger sugar highs, a mouse study shows.  

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image: Birth of the Skin Microbiome

Birth of the Skin Microbiome

By | November 17, 2015

The immune system tolerates the colonization of commensal bacteria on the skin with the aid of regulatory T cells during the first few weeks of life, a mouse study shows.

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image: Wiping Out Gut Bugs Stops Obesity

Wiping Out Gut Bugs Stops Obesity

By | November 16, 2015

In mice lacking intestinal microbiota, white fat turns brown and obesity is prevented.

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image: Another Telomere-Regulating Enzyme Found

Another Telomere-Regulating Enzyme Found

By | November 12, 2015

Researchers identify a novel protein that helps maintain the length of chromosome-capping telomeres. 

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image: Blood-Gut Barrier

Blood-Gut Barrier

By | November 12, 2015

Scientists identify a barrier in mice between the intestine and its blood supply, and suggest how Salmonella sneaks through it.

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image: Breaching the Blood-Brain Barrier

Breaching the Blood-Brain Barrier

By | November 11, 2015

Researchers deliver cancer-fighting drugs to a patient’s brain via the bloodstream, penetrating the blood-brain barrier for the first time.

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image: Week in Review: November 2–6

Week in Review: November 2–6

By | November 6, 2015

How Ebola hides from immune cells; gut microbes’ role in immunotherapy response; new mechanisms of hearing loss; butterflies use milkweed toxins to ward off predators

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image: Microbes Play Role in Anti-Tumor Response

Microbes Play Role in Anti-Tumor Response

By | November 5, 2015

Gut microbiome composition can influence the effectiveness of cancer immunotherapy in mice.

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image: New Route to Hearing Loss Mapped

New Route to Hearing Loss Mapped

By | November 5, 2015

Deficiency in a protein called pejvakin makes inner ear cells more vulnerable to sound, unable to brace themselves against oxidative stress stimulated by noise. 

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Horizon Discovery

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