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Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
The Infection-Chronic Disease Link Strengthens
Ricki Lewis | Sep 3, 2000 | 6 min read
Infection" is usually associated with an oozing sore, a bout with the flu, or an outbreak in some exotic place. But infectious organisms lie behind many chronic illnesses too, and an increasingly molecular approach to diagnosis is clarifying some of these relationships. An invited panel discussed "The Infectious Etiology of Chronic Diseases" at the second International Conference on Emerging Infectious Diseases, held in Atlanta July 16-19. Chronic diseases take a huge toll. "In the [United St
Who Sleeps?
The Scientist and Jerome Siegel | Mar 1, 2016 | 10+ min read
Once believed to be unique to birds and mammals, sleep is found across the metazoan kingdom. Some animals, it seems, can’t live without it, though no one knows exactly why.
New Molecular Tools Enable Researchers To Correlate Viruses, Diseases
Karen Young Kreeger | Feb 4, 1996 | 7 min read
Viruses, Diseases Author: Karen Young Kreeger Sidebar: Professional Resources for Viral Disease Researchers In the mid- to late 1980s, numerous correlations were discovered between viruses and various types of cancers. For example, Epstein-Barr virus was associated with nasopharyngeal carcinoma and B-cell lymphoma, hepatitis B virus with liver cancer, and human papillomavirus with cervical cancer. Now, a decade later, basic and clinical scientists are finding out that viruses may also play a r
Notebook
Paul Smaglik | Jul 4, 1999 | 7 min read
Contents Trial veteran Resistance in rivers I contain multitudes Chlamydia in heart disease Tomatoes vs. armyworms Look, Ma, no paws Peroxide damage Philip Brunell receives the first injection at NIH of the experimental shingles vaccine from nurse Patricia Hohman. TRIAL VETERAN When Philip Brunell received the first shingles vaccination in a Phase III trial June 17, it was not exactly a shot in the dark. The senior attending physician at the National Institutes of Health clinical center estim
Homing In On Homocysteine
Ricki Lewis | Jan 23, 2000 | 9 min read
Peruse the aisles of any supermarket, and the message that cholesterol causes heart disease rings loud and clear. But soon attention will likely shift to another culprit: homocysteine. This amino acid is usually scant in the blood. But when slightly elevated, it may set the stage for the atherosclerosis that is so tightly linked to cholesterol. Controlling homocysteine level is a simple matter of taking more vitamins--folic acid in particular. Donald Jacobsen "In the future, a homocysteine
Soybeans Hit Main Street
Barry Palevitz | Mar 19, 2000 | 8 min read
Once a favorite of Chinese emperors, tofu is now big time. From supermarkets to health food boutiques, diet-conscious Americans are buying soybeans, not just as tofu but in infant formula, soy milk, and soy burgers. Soy even has the Food and Drug Administration's seal of approval. Last October the FDA responded to a petition by Protein Technologies International, a St. Louis-based DuPont company specializing in soy products, by authorizing claims that soy protein is good for the heart. Acc
Notebook
Steve Bunk | Nov 7, 1999 | 7 min read
Content Jumping DNA Semen pharming Screening for heart risk Real-time signaling PubSCIENCE starts, PubMedCentral grows When time stands still Shutting down the pump Brain gain JUMPING DNA Mutations aren't transmitted only by inheritance--they can cross species, too, according to recent findings by John F. McDonald, head of the genetics department at the University of Georgia (I.K. Jordan et al., "Evidence for the recent horizontal transfer of long terminal repeat retrotransposon," Proceedings of
How Much Do Sex Differences Matter in Mouse Studies?
Joshua A. Krisch | Feb 23, 2017 | 4 min read
Examining both male and female model organisms is worth the extra effort and added costs, most experts maintain, but whether the results translate to human studies is less clear.
 
Ghosts in the Genome
Oliver J. Rando | Dec 1, 2015 | 10+ min read
How one generation’s experience can affect the next

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