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tag coronary heart disease culture evolution genetics genomics

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Layered visual representation of multiomics
Integrate and Innovate with NGS and Multiomics
The Scientist and Illumina | May 4, 2023 | 6 min read
Researchers across disciplines combine layers of discovery obtained with accessible NGS-based multiomics approaches.
On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.
Illustration showing a puzzle piece of DNA being removed
Large Scientific Collaborations Aim to Complete Human Genome
Brianna Chrisman and Jordan Eizenga | Sep 1, 2022 | 10+ min read
Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Evolving heart
Elie Dolgin | Aug 1, 2009 | 3 min read
By Elie Dolgin Evolving heart In 1948, 5,209 residents of a medium-sized New England town signed up for what would become the longest-running, systematic medical study in the world. The Framingham Heart Study, as it was called, was the first to show that smoking, obesity, and high cholesterol all increased people’s chances of developing heart disease. Six decades on, it’s also the first multigenerational human study to reveal that
Beyond the Blueprint
Jennifer A. Schweitzer, Mark A. Genung, and Joseph K. Bailey | Sep 1, 2014 | 10+ min read
In addition to serving as a set of instructions to build an individual, the genome can influence neighboring organisms and, potentially, entire ecosystems.
Genome Collector: A Profile of Charles Rotimi
Anna Azvolinsky | Oct 1, 2018 | 9 min read
The NIH epidemiologist has worked to ensure genetic health and population genetics studies contain data from African—not just European—populations.
Diseases by Design
Jennifer Fisher Wilson | Jun 1, 2003 | 6 min read
Jacob Halaska, ©Index Stock Imagery Researchers like mice. US government statistics reveal that the whiskered ones show up in 90% of all experiments. Mice come cheap, procreate often, and die fairly quickly. And although evolution separates mouse from human by an estimated 75 to 100 million years, biologically and genetically speaking, they share a lot; as much as 85% of the DNA in mice is the same in humans. The research ground that mice have domineered for a century, however, is reced
Cancer Researchers Use Evolution to Target Drug Resistance
Catherine Offord | Apr 1, 2020 | 10+ min read
New therapeutic approaches in oncology aim to manipulate or block cancer’s adaptation to treatment.

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