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tag coronary heart disease developmental biology genetics genomics culture

On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.
Advances in the functional characterization of newly discovered microproteins hint at their diverse roles  in health and disease
The Dark Matter of the Human Proteome
Annie Rathore | Apr 1, 2019 | 10 min read
Advances in the functional characterization of newly discovered microproteins hint at diverse roles in health and disease.
Can Genetics Explain Human Behavior?
Bill Sullivan | Sep 1, 2019 | 3 min read
The author of a new book about emerging concepts in human genetics considers the question.
Genome Collector: A Profile of Charles Rotimi
Anna Azvolinsky | Oct 1, 2018 | 9 min read
The NIH epidemiologist has worked to ensure genetic health and population genetics studies contain data from African—not just European—populations.
The dark matter of disease
Hannah Waters | Apr 24, 2011 | 5 min read
Scientists are beginning to unravel how non-coding DNA works across long distances of the genome to influence disease
GWAS, psychotic disorder, mood disorder, Q&A, bipolar disorder, schizophrenia, depression, sex differences
Genetic Variants Tied to Sex Differences in Psychiatric Disorders
Amanda Heidt | Mar 31, 2021 | 5 min read
The largest study of its kind identifies single nucleotide polymorphisms with disparate effects on men’s and women’s susceptibility to conditions such as bipolar disorder and schizophrenia.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Macrophages Are the Ultimate Multitaskers
Claire Asher | Oct 1, 2017 | 10+ min read
From guiding branching neurons in the developing brain to maintaining a healthy heartbeat, there seems to be no job that the immune cells can’t tackle.
Genetic Parasites and a Whole Lot More
Barry Palevitz | Oct 15, 2000 | 10+ min read
Photo: Ori Fragman, Hebrew University Hordeum spontaneum, the plant studied for BARE-1 retroelements. With genome sequences arriving almost as regularly as the morning paper, the public's attention is focused on genes--new genes to protect crops against pests; rogue genes that make bacteria resistant to antibiotics; faulty genes that, if fixed, could cure diseases such as muscular dystrophy. What many people don't realize is that genes account for only part of an organism's DNA, and in many c
New Light on Fetal Origins of Adult Disease
Ricki Lewis | Oct 29, 2000 | 5 min read
Human prenatal development can be viewed as a program of genetic switches that turn on, in a highly regulated manner, at specific places and times. But a body of evidence is emerging that paints a less hardwired picture, one of responses to environmental challenges fostering changes early on that reverberate decades later, in the guise of cardiovascular disease and diabetes. A symposium at the American Society of Human Genetics annual meeting, held in Philadelphia Oct. 3-7, addressed the fetal o

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