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Scientists are using a powerful gene editing technique to understand how human embryos develop.

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image: Gene Drive Limitations

Gene Drive Limitations

By | October 9, 2017

In lab populations of genetically engineered mosquitoes, mutations arose that blocked the gene drive’s spread and restored female fertility.

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image: CRISPR System Targets RNA in Mammalian Cells

CRISPR System Targets RNA in Mammalian Cells

By | October 4, 2017

Researchers engineer bacterial CRISPR-Cas13 to knock down RNA in mammalian cells.

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image: Nonviral CRISPR Delivery a Success

Nonviral CRISPR Delivery a Success

By | October 2, 2017

Researchers use gold nanoparticles to deliver CRISPR-Cas9 and correct a point mutation in a mouse model of Duchenne muscular dystrophy. 

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image: Flux and Uncertainty in the CRISPR Patent Landscape

Flux and Uncertainty in the CRISPR Patent Landscape

By | October 1, 2017

The battle for the control of the intellectual property surrounding CRISPR-Cas9 is as storied and nuanced as the technology itself.

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image: Book Excerpt from <em>Rise of the Necrofauna</em>

Book Excerpt from Rise of the Necrofauna

By | October 1, 2017

In chapter 4, “Why Recreate the Woolly Mammoth?” author Britt Wray explores the social consequences of bringing an iconic species back from extinction.

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Researchers use base-editing to swap out an erroneous nucleotide responsible for a potentially life-threatening blood disorder.

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image: Most Accurate CRISPR Gene Editing Yet

Most Accurate CRISPR Gene Editing Yet

By | September 22, 2017

A tweaked Cas9 nuclease reduces off-target effects to levels below that of previous versions of the enzyme.

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image: CRISPR Used in Human Embryos to Probe Gene Function

CRISPR Used in Human Embryos to Probe Gene Function

By | September 20, 2017

OCT4 is necessary for blastocyst formation in the human embryo, researchers report.

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image: CRISPR May Prove Useful in De-Extinction Efforts

CRISPR May Prove Useful in De-Extinction Efforts

By | September 1, 2017

Researchers are using the powerful gene-editing tool to recreate the woolly mammoth.

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