The Scientist

» CRISPR

Most Recent

image: Was a Drop in CRISPR Firms’ Stock Warranted?

Was a Drop in CRISPR Firms’ Stock Warranted?

By | June 7, 2017

A study of off-target effects that sparked fear among investors of genome-editing companies receives methodological criticisms.

5 Comments

Scientists hope to save oranges from a bacterial disease that causes citrus greening, a disease that leads to bitter, discolored fruit.

1 Comment

image: RNAi’s Future in Drug-Target Screening

RNAi’s Future in Drug-Target Screening

By | April 17, 2017

A recent CRISPR study contradicted years of RNA interference research on a well-studied cancer drug target. But is it the last nail in the coffin for RNAi as a screening tool? 

0 Comments

image: CRISPR-Based Nucleic Acid Test Debuts

CRISPR-Based Nucleic Acid Test Debuts

By | April 13, 2017

SHERLOCK combines CRISPR-Cas13a with isothermal RNA amplification to detect RNA and DNA with single-base specificity.

0 Comments

image: CRISPR Corrects Duchenne-Causing Mutations

CRISPR Corrects Duchenne-Causing Mutations

By | April 12, 2017

Using CRISPR-Cpf1 gene editing, researchers have fixed mutations that cause a form of muscular dystrophy in cultured human cardiomyocytes and a mouse model.

0 Comments

image: CRISPR Screen Detects Functional Gene Regulation

CRISPR Screen Detects Functional Gene Regulation

By | April 3, 2017

A CRISPR-Cas9–based method probes the regulatory roles of noncoding DNA sequences.

0 Comments

image: Rethinking a Cancer Drug Target

Rethinking a Cancer Drug Target

By | March 26, 2017

The results of a CRISPR-Cas9 study suggest that MELK—a protein thought to play a critical role in cancer—is not necessary for cancer cell survival.

0 Comments

image: UC Berkeley Receives CRISPR Patent in Europe

UC Berkeley Receives CRISPR Patent in Europe

By | March 24, 2017

The European Patent Office will grant patent rights over the use of CRISPR in all cell types to a University of California team, contrasting with a recent decision in the U.S.

3 Comments

image: A Selection of CRISPR Proof-of-Principle Studies

A Selection of CRISPR Proof-of-Principle Studies

By | March 1, 2017

Advice on how to deploy the latest techniques in your own lab

0 Comments

image: Massively Parallel Perturbations

Massively Parallel Perturbations

By | March 1, 2017

Scientists combine CRISPR gene editing with single-cell sequencing for genotype-phenotype screens.

0 Comments

Popular Now

  1. Running on Empty
    Features Running on Empty

    Regularly taking breaks from eating—for hours or days—can trigger changes both expected, such as in metabolic dynamics and inflammation, and surprising, as in immune system function and cancer progression.

  2. Athletes’ Microbiomes Differ from Nonathletes
  3. Stomach Cells Change Identity to Drive Precancerous State
  4. Mutation Linked to Longer Life Span in Men
AAAS